In this review, we discuss approaches for learning causal structure from data, also called causal discovery. In particular, we focus on approaches for learning directed acyclic graphs (DAGs) and various generalizations which allow for some variables to be unobserved in the available data. We devote special attention to two fundamental combinatorial aspects of causal structure learning. First, we discuss the structure of the search space over causal graphs. Second, we discuss the structure of equivalence classes over causal graphs, i.e., sets of graphs which represent what can be learned from observational data alone, and how these equivalence classes can be refined by adding interventional data.
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我们考虑代表代理模型的问题,该模型使用我们称之为CSTREES的阶段树模型的适当子类对离散数据编码离散数据的原因模型。我们表明,可以通过集合表达CSTREE编码的上下文专用信息。由于并非所有阶段树模型都承认此属性,CSTREES是一个子类,可提供特定于上下文的因果信息的透明,直观和紧凑的表示。我们证明了CSTREEES承认全球性马尔可夫属性,它产生了模型等价的图形标准,概括了Verma和珍珠的DAG模型。这些结果延伸到一般介入模型设置,使CSTREES第一族的上下文专用模型允许介入模型等价的特征。我们还为CSTREE的最大似然估计器提供了一种封闭式公式,并使用它来表示贝叶斯信息标准是该模型类的本地一致的分数函数。在模拟和实际数据上分析了CSTHEELE的性能,在那里我们看到与CSTREELE而不是一般上演树的建模不会导致预测精度的显着损失,同时提供了特定于上下文的因果信息的DAG表示。
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贝叶斯网络是概率的图形模型,广泛用于了解高维数据的依赖关系,甚至促进因果发现。学习作为定向的非循环图(DAG)编码的底层网络结构是高度具有挑战性的,主要是由于大量可能的网络与非狭窄性约束结合。努力专注于两个前面:基于约束的方法,该方法执行条件独立测试,以排除具有贪婪或MCMC方案的DAG空间的边缘和分数和搜索方法。在这里,我们以一种新的混合方法综合这两个领域,这降低了基于约束方法的MCMC方法的复杂性。 MCMC方案中的各个步骤仅需要简单的表查找,以便可以有效地获得非常长的链。此外,该方案包括迭代过程,以校正来自条件独立测试的错误。该算法对替代方案提供了显着卓越的性能,特别是因为也可以从后部分布采样DAG,从而实现全面的贝叶斯模型为大量较大的贝叶斯网络进行平均。
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We consider the problem of recovering the causal structure underlying observations from different experimental conditions when the targets of the interventions in each experiment are unknown. We assume a linear structural causal model with additive Gaussian noise and consider interventions that perturb their targets while maintaining the causal relationships in the system. Different models may entail the same distributions, offering competing causal explanations for the given observations. We fully characterize this equivalence class and offer identifiability results, which we use to derive a greedy algorithm called GnIES to recover the equivalence class of the data-generating model without knowledge of the intervention targets. In addition, we develop a novel procedure to generate semi-synthetic data sets with known causal ground truth but distributions closely resembling those of a real data set of choice. We leverage this procedure and evaluate the performance of GnIES on synthetic, real, and semi-synthetic data sets. Despite the strong Gaussian distributional assumption, GnIES is robust to an array of model violations and competitive in recovering the causal structure in small- to large-sample settings. We provide, in the Python packages "gnies" and "sempler", implementations of GnIES and our semi-synthetic data generation procedure.
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本文考虑了从观察和介入数据估算因果导向的非循环图中未知干预目标的问题。重点是线性结构方程模型(SEM)中的软干预。目前对因果结构的方法学习使用已知的干预目标或使用假设测试来发现即使是线性SEM也可以发现未知的干预目标。这严重限制了它们的可扩展性和样本复杂性。本文提出了一种可扩展和高效的算法,始终识别所有干预目标。关键思想是从与观察和介入数据集相关联的精度矩阵之间的差异来估计干预站点。它涉及反复估计不同亚空间子集中的这些站点。该算法的算法还可用于将给定的观察马尔可夫等效类更新为介入马尔可夫等价类。在分析地建立一致性,马尔可夫等效和采样复杂性。最后,实际和合成数据的仿真结果展示了所提出的可扩展因果结构恢复方法的增益。算法的实现和重现仿真结果的代码可用于\ url {https://github.com/bvarici/intervention- istimation}。
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也称为(非参数)结构方程模型(SEMS)的结构因果模型(SCM)被广泛用于因果建模目的。特别是,也称为递归SEM的无循环SCMS,形成了一个研究的SCM的良好的子类,概括了因果贝叶斯网络来允许潜在混淆。在本文中,我们调查了更多普通环境中的SCM,允许存在潜在混杂器和周期。我们展示在存在周期中,无循环SCM的许多方便的性质通常不会持有:它们并不总是有解决方案;它们并不总是诱导独特的观察,介入和反事实分布;边缘化并不总是存在,如果存在边缘模型并不总是尊重潜在的投影;他们并不总是满足马尔可夫财产;他们的图表并不总是与他们的因果语义一致。我们证明,对于SCM一般,这些属性中的每一个都在某些可加工条件下保持。我们的工作概括了SCM的结果,迄今为止仅针对某些特殊情况所知的周期。我们介绍了将循环循环设置扩展到循环设置的简单SCM的类,同时保留了许多方便的无环SCM的性能。用本文,我们的目标是为SCM提供统计因果建模的一般理论的基础。
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In this paper we prove the so-called "Meek Conjecture". In particular, we show that if a DAG H is an independence map of another DAG G, then there exists a finite sequence of edge additions and covered edge reversals in G such that (1) after each edge modification H remains an independence map of G and ( 2) after all modifications G = H. As shown by Meek (1997), this result has an important consequence for Bayesian approaches to learning Bayesian networks from data: in the limit of large sample size, there exists a twophase greedy search algorithm that-when applied to a particular sparsely-connected search space-provably identifies a perfect map of the generative distribution if that perfect map is a DAG. We provide a new implementation of the search space, using equivalence classes as states, for which all operators used in the greedy search can be scored efficiently using local functions of the nodes in the domain. Finally, using both synthetic and real-world datasets, we demonstrate that the two-phase greedy approach leads to good solutions when learning with finite sample sizes.
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因果关系是理解世界的科学努力的基本组成部分。不幸的是,在心理学和社会科学中,因果关系仍然是禁忌。由于越来越多的建议采用因果方法进行研究的重要性,我们重新制定了心理学研究方法的典型方法,以使不可避免的因果理论与其余的研究渠道协调。我们提出了一个新的过程,该过程始于从因果发现和机器学习的融合中纳入技术的发展,验证和透明的理论形式规范。然后,我们提出将完全指定的理论模型的复杂性降低到与给定目标假设相关的基本子模型中的方法。从这里,我们确定利息量是否可以从数据中估算出来,如果是的,则建议使用半参数机器学习方法来估计因果关系。总体目标是介绍新的研究管道,该管道可以(a)促进与测试因果理论的愿望兼容的科学询问(b)鼓励我们的理论透明代表作为明确的数学对象,(c)将我们的统计模型绑定到我们的统计模型中该理论的特定属性,因此减少了理论到模型间隙通常引起的规范不足问题,以及(d)产生因果关系和可重复性的结果和估计。通过具有现实世界数据的教学示例来证明该过程,我们以摘要和讨论来结论。
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最近对DataSet Shift的兴趣,已经产生了许多方法,用于查找新的未经,无奈环境中预测的不变分布。然而,这些方法考虑不同类型的班次,并且已经在不同的框架下开发,从理论上难以分析解决方案如何与稳定性和准确性不同。采取因果图形视图,我们使用灵活的图形表示来表达各种类型的数据集班次。我们表明所有不变的分布对应于图形运算符的因果层次结构,该图形运算符禁用负责班次的图表中的边缘。层次结构提供了一个常见的理论基础,以便理解可以实现转移的何时以及如何实现稳定性,并且在稳定的分布可能不同的情况下。我们使用它来建立跨环境最佳性能的条件,并导出找到最佳稳定分布的新算法。使用这种新的视角,我们经验证明了最低限度和平均性能之间的权衡。
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考虑基于AI和ML的决策对这些新兴技术的安全和可接受的使用的决策的社会和道德后果至关重要。公平,特别是保证ML决定不会导致对个人或少数群体的歧视。使用因果关系,可以更好地实现和衡量可靠的公平/歧视,从而更好地实现了敏感属性(例如性别,种族,宗教等)之间的因果关系,仅仅是仅仅是关联,例如性别,种族,宗教等(例如,雇用工作,贷款授予等) )。然而,对因果关系解决公平性的最大障碍是因果模型的不可用(通常表示为因果图)。文献中现有的因果关系方法并不能解决此问题,并假设可获得因果模型。在本文中,我们没有做出这样的假设,并且我们回顾了从可观察数据中发现因果关系的主要算法。这项研究的重点是因果发现及其对公平性的影响。特别是,我们展示了不同的因果发现方法如何导致不同的因果模型,最重要的是,即使因果模型之间的轻微差异如何对公平/歧视结论产生重大影响。通过使用合成和标准公平基准数据集的经验分析来巩固这些结果。这项研究的主要目标是强调因果关系使用因果关系适当解决公平性的因果发现步骤的重要性。
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因果结构学习是许多领域的关键问题。通过对感兴趣系统进行实验来学习因果结构。我们解决了设计一批实验的主要原因,每个实验中同时干预多个变量。虽然可能比常用的单变干预措施更具信息丰富,但选择这种干预措施是更具挑战性的,这是由于复合干预措施的双指数组合搜索空间。在本文中,我们开发有效的算法,以优化量化预算限制批次实验的信息性的不同目标函数。通过建立这些目标的新型子模具性质,我们为我们的算法提供近似保证。我们的算法经验上优于随机干预和算法,只能选择单变化干预。
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We explore how observational and interventional causal discovery methods can be combined. A state-of-the-art observational causal discovery algorithm for time series capable of handling latent confounders and contemporaneous effects, called LPCMCI, is extended to profit from casual constraints found through randomized control trials. Numerical results show that, given perfect interventional constraints, the reconstructed structural causal models (SCMs) of the extended LPCMCI allow 84.6% of the time for the optimal prediction of the target variable. The implementation of interventional and observational causal discovery is modular, allowing causal constraints from other sources. The second part of this thesis investigates the question of regret minimizing control by simultaneously learning a causal model and planning actions through the causal model. The idea is that an agent to optimize a measured variable first learns the system's mechanics through observational causal discovery. The agent then intervenes on the most promising variable with randomized values allowing for the exploitation and generation of new interventional data. The agent then uses the interventional data to enhance the causal model further, allowing improved actions the next time. The extended LPCMCI can be favorable compared to the original LPCMCI algorithm. The numerical results show that detecting and using interventional constraints leads to reconstructed SCMs that allow 60.9% of the time for the optimal prediction of the target variable in contrast to the baseline of 53.6% when using the original LPCMCI algorithm. Furthermore, the induced average regret decreases from 1.2 when using the original LPCMCI algorithm to 1.0 when using the extended LPCMCI algorithm with interventional discovery.
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人们对利用置换推理来搜索定向的无环因果模型的方法越来越兴趣,包括Teysier和Kohler和Solus,Wang和Uhler的GSP的“订购搜索”。我们通过基于置换的操作Tuck扩展了后者的方法,并开发了一类算法,即掌握,这些算法在越来越弱的假设下比忠诚度更有效且方向保持一致。最放松的掌握形式优于模拟中许多最新的因果搜索算法,即使对于具有超过100个变量的密集图和图形,也可以有效,准确地搜索。
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跨学科的一个重要问题是发现产生预期结果的干预措施。当可能的干预空间很大时,需要进行详尽的搜索,需要实验设计策略。在这种情况下,编码变量之间的因果关系以及因此对系统的影响,对于有效地确定理想的干预措施至关重要。我们开发了一种迭代因果方法来识别最佳干预措施,这是通过分布后平均值和所需目标平均值之间的差异来衡量的。我们制定了一种主动学习策略,该策略使用从不同干预措施中获得的样本来更新有关基本因果模型的信念,并确定对最佳干预措施最有用的样本,因此应在下一批中获得。该方法采用了因果模型的贝叶斯更新,并使用精心设计的,有因果关系的收购功能优先考虑干预措施。此采集函数以封闭形式进行评估,从而有效优化。理论上以信息理论界限和可证明的一致性结果在理论上基于理论上的算法。我们说明了综合数据和现实世界生物学数据的方法,即来自worturb-cite-seq实验的基因表达数据,以识别诱导特定细胞态过渡的最佳扰动;与几个基线相比,观察到所提出的因果方法可实现更好的样品效率。在这两种情况下,我们都认为因果知情的采集函数尤其优于现有标准,从而允许使用实验明显更少的最佳干预设计。
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我们分析了在没有特定分布假设的常规设置中从观察数据的学习中学循环图形模型的复杂性。我们的方法是信息定理,并使用本地马尔可夫边界搜索程序,以便在基础图形模型中递归地构建祖先集。也许令人惊讶的是,我们表明,对于某些图形集合,一个简单的前向贪婪搜索算法(即没有向后修剪阶段)足以学习每个节点的马尔可夫边界。这显着提高了我们在节点的数量中显示的样本复杂性。然后应用这一点以在从文献中概括存在现有条件的新型标识性条件下学习整个图。作为独立利益的问题,我们建立了有限样本的保障,以解决从数据中恢复马尔可夫边界的问题。此外,我们将我们的结果应用于特殊情况的Polytrees,其中假设简化,并提供了多项识别的明确条件,并且在多项式时间中可以识别和可知。我们进一步说明了算法在仿真研究中易于实现的算法的性能。我们的方法是普遍的,用于无需分布假设的离散或连续分布,并且由于这种棚灯对有效地学习来自数据的定向图形模型结构所需的最小假设。
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We study experiment design for unique identification of the causal graph of a system where the graph may contain cycles. The presence of cycles in the structure introduces major challenges for experiment design as, unlike acyclic graphs, learning the skeleton of causal graphs with cycles may not be possible from merely the observational distribution. Furthermore, intervening on a variable in such graphs does not necessarily lead to orienting all the edges incident to it. In this paper, we propose an experiment design approach that can learn both cyclic and acyclic graphs and hence, unifies the task of experiment design for both types of graphs. We provide a lower bound on the number of experiments required to guarantee the unique identification of the causal graph in the worst case, showing that the proposed approach is order-optimal in terms of the number of experiments up to an additive logarithmic term. Moreover, we extend our result to the setting where the size of each experiment is bounded by a constant. For this case, we show that our approach is optimal in terms of the size of the largest experiment required for uniquely identifying the causal graph in the worst case.
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因果推断的一个共同主题是学习观察到的变量(也称为因果发现)之间的因果关系。考虑到大量候选因果图和搜索空间的组合性质,这通常是一项艰巨的任务。也许出于这个原因,到目前为止,大多数研究都集中在相对较小的因果图上,并具有多达数百个节点。但是,诸如生物学之类的领域的最新进展使生成实验数据集,并进行了数千种干预措施,然后进行了数千个变量的丰富分析,从而增加了机会和迫切需要大量因果图模型。在这里,我们介绍了因子定向无环图(F-DAG)的概念,是将搜索空间限制为非线性低级别因果相互作用模型的一种方法。将这种新颖的结构假设与最近的进步相结合,弥合因果发现与连续优化之间的差距,我们在数千个变量上实现了因果发现。此外,作为统计噪声对此估计程序的影响的模型,我们根据随机图研究了F-DAG骨架的边缘扰动模型,并量化了此类扰动对F-DAG等级的影响。该理论分析表明,一组候选F-DAG比整个DAG空间小得多,因此在很难评估基础骨架的高维度中更统计学上的稳定性。我们提出了因子图(DCD-FG)的可区分因果发现,这是对高维介入数据的F-DAG约束因果发现的可扩展实现。 DCD-FG使用高斯非线性低级结构方程模型,并且在模拟中的最新方法以及最新的大型单细胞RNA测序数据集中,与最新方法相比显示出显着改善遗传干预措施。
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Bayesian causal structure learning aims to learn a posterior distribution over directed acyclic graphs (DAGs), and the mechanisms that define the relationship between parent and child variables. By taking a Bayesian approach, it is possible to reason about the uncertainty of the causal model. The notion of modelling the uncertainty over models is particularly crucial for causal structure learning since the model could be unidentifiable when given only a finite amount of observational data. In this paper, we introduce a novel method to jointly learn the structure and mechanisms of the causal model using Variational Bayes, which we call Variational Bayes-DAG-GFlowNet (VBG). We extend the method of Bayesian causal structure learning using GFlowNets to learn not only the posterior distribution over the structure, but also the parameters of a linear-Gaussian model. Our results on simulated data suggest that VBG is competitive against several baselines in modelling the posterior over DAGs and mechanisms, while offering several advantages over existing methods, including the guarantee to sample acyclic graphs, and the flexibility to generalize to non-linear causal mechanisms.
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Learning causal structure from observational data often assumes that we observe independent and identically distributed (i.\,i.\,d) data. The traditional approach aims to find a graphical representation that encodes the same set of conditional independence relationships as those present in the observed distribution. It is known that under i.\,i.\,d assumption, even with infinite data, there is a limit to how fine-grained a causal structure we can identify. To overcome this limitation, recent work has explored using data originating from different, related environments to learn richer causal structure. These approaches implicitly rely on the independent causal mechanisms (ICM) principle, which postulates that the mechanism giving rise to an effect given its causes and the mechanism which generates the causes do not inform or influence each other. Thus, components of the causal model can independently change from environment to environment. Despite its wide application in machine learning and causal inference, there is a lack of statistical formalization of the ICM principle and how it enables identification of richer causal structures from grouped data. Here we present new causal de Finetti theorems which offer a first statistical formalization of ICM principle and show how causal structure identification is possible from exchangeable data. Our work provides theoretical justification for a broad range of techniques leveraging multi-environment data to learn causal structure.
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因果推断对于跨业务参与,医疗和政策制定等领域的数据驱动决策至关重要。然而,关于因果发现的研究已经与推理方法分开发展,从而阻止了两个领域方法的直接组合。在这项工作中,我们开发了深层端到端因果推理(DECI),这是一种基于流动的非线性添加噪声模型,该模型具有观察数据,并且可以执行因果发现和推理,包括有条件的平均治疗效果(CATE) )估计。我们提供了理论上的保证,即DECI可以根据标准因果发现假设恢复地面真实因果图。受应用影响的激励,我们将该模型扩展到具有缺失值的异质,混合型数据,从而允许连续和离散的治疗决策。我们的结果表明,与因果发现的相关基线相比,DECI的竞争性能和(c)在合成数据集和因果机器学习基准测试基准的一千多个实验中,跨数据类型和缺失水平进行了估计。
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