Morality in dialogue systems has raised great attention in research recently. A moral dialogue system could better connect users and enhance conversation engagement by gaining users' trust. In this paper, we propose a framework, MoralDial to train and evaluate moral dialogue systems. In our framework, we first explore the communication mechanisms of morality and resolve expressed morality into four sub-modules. The sub-modules indicate the roadmap for building a moral dialogue system. Based on that, we design a simple yet effective method: constructing moral discussions from Rules of Thumb (RoTs) between simulated specific users and the dialogue system. The constructed discussion consists of expressing, explaining, and revising the moral views in dialogue exchanges, which makes conversational models learn morality well in a natural manner. Furthermore, we propose a novel evaluation method in the framework. We evaluate the multiple aspects of morality by judging the relation between dialogue responses and RoTs in discussions, where the multifaceted nature of morality is particularly considered. Automatic and manual experiments demonstrate that our framework is promising to train and evaluate moral dialogue systems.

With the continuously thriving popularity around the world, fitness activity analytic has become an emerging research topic in computer vision. While a variety of new tasks and algorithms have been proposed recently, there are growing hunger for data resources involved in high-quality data, fine-grained labels, and diverse environments. In this paper, we present FLAG3D, a large-scale 3D fitness activity dataset with language instruction containing 180K sequences of 60 categories. FLAG3D features the following three aspects: 1) accurate and dense 3D human pose captured from advanced MoCap system to handle the complex activity and large movement, 2) detailed and professional language instruction to describe how to perform a specific activity, 3) versatile video resources from a high-tech MoCap system, rendering software, and cost-effective smartphones in natural environments. Extensive experiments and in-depth analysis show that FLAG3D contributes great research value for various challenges, such as cross-domain human action recognition, dynamic human mesh recovery, and language-guided human action generation. Our dataset and source code will be publicly available at https://andytang15.github.io/FLAG3D.

We study a challenging task, conditional human motion generation, which produces plausible human motion sequences according to various conditional inputs, such as action classes or textual descriptors. Since human motions are highly diverse and have a property of quite different distribution from conditional modalities, such as textual descriptors in natural languages, it is hard to learn a probabilistic mapping from the desired conditional modality to the human motion sequences. Besides, the raw motion data from the motion capture system might be redundant in sequences and contain noises; directly modeling the joint distribution over the raw motion sequences and conditional modalities would need a heavy computational overhead and might result in artifacts introduced by the captured noises. To learn a better representation of the various human motion sequences, we first design a powerful Variational AutoEncoder (VAE) and arrive at a representative and low-dimensional latent code for a human motion sequence. Then, instead of using a diffusion model to establish the connections between the raw motion sequences and the conditional inputs, we perform a diffusion process on the motion latent space. Our proposed Motion Latent-based Diffusion model (MLD) could produce vivid motion sequences conforming to the given conditional inputs and substantially reduce the computational overhead in both the training and inference stages. Extensive experiments on various human motion generation tasks demonstrate that our MLD achieves significant improvements over the state-of-the-art methods among extensive human motion generation tasks, with two orders of magnitude faster than previous diffusion models on raw motion sequences.

Low-dose computed tomography (CT) plays a significant role in reducing the radiation risk in clinical applications. However, lowering the radiation dose will significantly degrade the image quality. With the rapid development and wide application of deep learning, it has brought new directions for the development of low-dose CT imaging algorithms. Therefore, we propose a fully unsupervised one sample diffusion model (OSDM)in projection domain for low-dose CT reconstruction. To extract sufficient prior information from single sample, the Hankel matrix formulation is employed. Besides, the penalized weighted least-squares and total variation are introduced to achieve superior image quality. Specifically, we first train a score-based generative model on one sinogram by extracting a great number of tensors from the structural-Hankel matrix as the network input to capture prior distribution. Then, at the inference stage, the stochastic differential equation solver and data consistency step are performed iteratively to obtain the sinogram data. Finally, the final image is obtained through the filtered back-projection algorithm. The reconstructed results are approaching to the normal-dose counterparts. The results prove that OSDM is practical and effective model for reducing the artifacts and preserving the image quality.

The discovery of drug-target interactions (DTIs) is a pivotal process in pharmaceutical development. Computational approaches are a promising and efficient alternative to tedious and costly wet-lab experiments for predicting novel DTIs from numerous candidates. Recently, with the availability of abundant heterogeneous biological information from diverse data sources, computational methods have been able to leverage multiple drug and target similarities to boost the performance of DTI prediction. Similarity integration is an effective and flexible strategy to extract crucial information across complementary similarity views, providing a compressed input for any similarity-based DTI prediction model. However, existing similarity integration methods filter and fuse similarities from a global perspective, neglecting the utility of similarity views for each drug and target. In this study, we propose a Fine-Grained Selective similarity integration approach, called FGS, which employs a local interaction consistency-based weight matrix to capture and exploit the importance of similarities at a finer granularity in both similarity selection and combination steps. We evaluate FGS on five DTI prediction datasets under various prediction settings. Experimental results show that our method not only outperforms similarity integration competitors with comparable computational costs, but also achieves better prediction performance than state-of-the-art DTI prediction approaches by collaborating with conventional base models. Furthermore, case studies on the analysis of similarity weights and on the verification of novel predictions confirm the practical ability of FGS.

The ubiquity of camera-embedded devices and the advances in deep learning have stimulated various intelligent mobile video applications. These applications often demand on-device processing of video streams to deliver real-time, high-quality services for privacy and robustness concerns. However, the performance of these applications is constrained by the raw video streams, which tend to be taken with small-aperture cameras of ubiquitous mobile platforms in dim light. Despite extensive low-light video enhancement solutions, they are unfit for deployment to mobile devices due to their complex models and and ignorance of system dynamics like energy budgets. In this paper, we propose AdaEnlight, an energy-aware low-light video stream enhancement system on mobile devices. It achieves real-time video enhancement with competitive visual quality while allowing runtime behavior adaptation to the platform-imposed dynamic energy budgets. We report extensive experiments on diverse datasets, scenarios, and platforms and demonstrate the superiority of AdaEnlight compared with state-of-the-art low-light image and video enhancement solutions.

Open Information Extraction (OpenIE) facilitates the open-domain discovery of textual facts. However, the prevailing solutions evaluate OpenIE models on in-domain test sets aside from the training corpus, which certainly violates the initial task principle of domain-independence. In this paper, we propose to advance OpenIE towards a more realistic scenario: generalizing over unseen target domains with different data distributions from the source training domains, termed Generalized OpenIE. For this purpose, we first introduce GLOBE, a large-scale human-annotated multi-domain OpenIE benchmark, to examine the robustness of recent OpenIE models to domain shifts, and the relative performance degradation of up to 70% implies the challenges of generalized OpenIE. Then, we propose DragonIE, which explores a minimalist graph expression of textual fact: directed acyclic graph, to improve the OpenIE generalization. Extensive experiments demonstrate that DragonIE beats the previous methods in both in-domain and out-of-domain settings by as much as 6.0% in F1 score absolutely, but there is still ample room for improvement.

Humans can balance very well during walking, even when perturbed. But it seems difficult to achieve robust walking for bipedal robots. Here we describe the simplest balance controller that leads to robust walking for a linear inverted pendulum (LIP) model. The main idea is to use a linear function of the body velocity to determine the next foot placement, which we call linear foot placement control (LFPC). By using the Poincar\'e map, a balance criterion is derived, which shows that LFPC is stable when the velocity-feedback coefficient is located in a certain range. And that range is much bigger when stepping faster, which indicates "faster stepping, easier to balance". We show that various gaits can be generated by adjusting the controller parameters in LFPC. Particularly, a dead-beat controller is discovered that can lead to steady-state walking in just one step. The effectiveness of LFPC is verified through Matlab simulation as well as V-REP simulation for both 2D and 3D walking. The main feature of LFPC is its simplicity and inherent robustness, which may help us understand the essence of how to maintain balance in dynamic walking.

Graph neural networks (GNNs) have been successfully applied to early mild cognitive impairment (EMCI) detection, with the usage of elaborately designed features constructed from blood oxygen level-dependent (BOLD) time series. However, few works explored the feasibility of using BOLD signals directly as features. Meanwhile, existing GNN-based methods primarily rely on hand-crafted explicit brain topology as the adjacency matrix, which is not optimal and ignores the implicit topological organization of the brain. In this paper, we propose a spatial temporal graph convolutional network with a novel graph structure self-learning mechanism for EMCI detection. The proposed spatial temporal graph convolution block directly exploits BOLD time series as input features, which provides an interesting view for rsfMRI-based preclinical AD diagnosis. Moreover, our model can adaptively learn the optimal topological structure and refine edge weights with the graph structure self-learning mechanism. Results on the Alzheimer's Disease Neuroimaging Initiative (ADNI) database show that our method outperforms state-of-the-art approaches. Biomarkers consistent with previous studies can be extracted from the model, proving the reliable interpretability of our method.

Partial label learning (PLL) is a typical weakly supervised learning, where each sample is associated with a set of candidate labels. The basic assumption of PLL is that the ground-truth label must reside in the candidate set. However, this assumption may not be satisfied due to the unprofessional judgment of the annotators, thus limiting the practical application of PLL. In this paper, we relax this assumption and focus on a more general problem, noisy PLL, where the ground-truth label may not exist in the candidate set. To address this challenging problem, we further propose a novel framework called "Automatic Refinement Network (ARNet)". Our method consists of multiple rounds. In each round, we purify the noisy samples through two key modules, i.e., noisy sample detection and label correction. To guarantee the performance of these modules, we start with warm-up training and automatically select the appropriate correction epoch. Meanwhile, we exploit data augmentation to further reduce prediction errors in ARNet. Through theoretical analysis, we prove that our method is able to reduce the noise level of the dataset and eventually approximate the Bayes optimal classifier. To verify the effectiveness of ARNet, we conduct experiments on multiple benchmark datasets. Experimental results demonstrate that our ARNet is superior to existing state-of-the-art approaches in noisy PLL. Our code will be made public soon.