A common assumption in causal inference from observational data is that there is no hidden confounding. Yet it is, in general, impossible to verify the presence of hidden confounding factors from a single dataset. Under the assumption of independent causal mechanisms underlying the data generating process, we demonstrate a way to detect unobserved confounders when having multiple observational datasets coming from different environments. We present a theory for testable conditional independencies that are only absent during hidden confounding and examine cases where we violate its assumptions: degenerate & dependent mechanisms, and faithfulness violations. Additionally, we propose a procedure to test these independencies and study its empirical finite-sample behavior using simulation studies and semi-synthetic data based on a real-world dataset. In most cases, our theory correctly predicts the presence of hidden confounding, particularly when the confounding bias is~large.
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因果关系是理解世界的科学努力的基本组成部分。不幸的是,在心理学和社会科学中,因果关系仍然是禁忌。由于越来越多的建议采用因果方法进行研究的重要性,我们重新制定了心理学研究方法的典型方法,以使不可避免的因果理论与其余的研究渠道协调。我们提出了一个新的过程,该过程始于从因果发现和机器学习的融合中纳入技术的发展,验证和透明的理论形式规范。然后,我们提出将完全指定的理论模型的复杂性降低到与给定目标假设相关的基本子模型中的方法。从这里,我们确定利息量是否可以从数据中估算出来,如果是的,则建议使用半参数机器学习方法来估计因果关系。总体目标是介绍新的研究管道,该管道可以(a)促进与测试因果理论的愿望兼容的科学询问(b)鼓励我们的理论透明代表作为明确的数学对象,(c)将我们的统计模型绑定到我们的统计模型中该理论的特定属性,因此减少了理论到模型间隙通常引起的规范不足问题,以及(d)产生因果关系和可重复性的结果和估计。通过具有现实世界数据的教学示例来证明该过程,我们以摘要和讨论来结论。
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估计平均因果效应的理想回归(如果有)是什么?我们在离散协变量的设置中研究了这个问题,从而得出了各种分层估计器的有限样本方差的表达式。这种方法阐明了许多广泛引用的结果的基本统计现象。我们的博览会结合了研究因果效应估计的三种不同的方法论传统的见解:潜在结果,因果图和具有加性误差的结构模型。
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This review presents empirical researchers with recent advances in causal inference, and stresses the paradigmatic shifts that must be undertaken in moving from traditional statistical analysis to causal analysis of multivariate data. Special emphasis is placed on the assumptions that underly all causal inferences, the languages used in formulating those assumptions, the conditional nature of all causal and counterfactual claims, and the methods that have been developed for the assessment of such claims. These advances are illustrated using a general theory of causation based on the Structural Causal Model (SCM) described in Pearl (2000a), which subsumes and unifies other approaches to causation, and provides a coherent mathematical foundation for the analysis of causes and counterfactuals. In particular, the paper surveys the development of mathematical tools for inferring (from a combination of data and assumptions) answers to three types of causal queries: (1) queries about the effects of potential interventions, (also called "causal effects" or "policy evaluation") (2) queries about probabilities of counterfactuals, (including assessment of "regret," "attribution" or "causes of effects") and (3) queries about direct and indirect effects (also known as "mediation"). Finally, the paper defines the formal and conceptual relationships between the structural and potential-outcome frameworks and presents tools for a symbiotic analysis that uses the strong features of both.
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尽管在治疗和结果之间存在未衡量的混杂因素,但前门标准可用于识别和计算因果关系。但是,关键假设 - (i)存在充分介导治疗对结果影响的变量(或一组变量)的存在,(ii)同时并不遭受类似的混淆问题的困扰 - outcome对 - 通常被认为是难以置信的。本文探讨了这些假设的可检验性。我们表明,在涉及辅助变量的轻度条件下,可以通过广义平等约束也可以测试前门模型中编码的假设(以及简单的扩展)。我们基于此观察结果提出了两个合适性测试,并评估我们对真实和合成数据的提议的疗效。我们还将理论和经验比较与仪器可变方法处理未衡量的混杂。
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We explore how observational and interventional causal discovery methods can be combined. A state-of-the-art observational causal discovery algorithm for time series capable of handling latent confounders and contemporaneous effects, called LPCMCI, is extended to profit from casual constraints found through randomized control trials. Numerical results show that, given perfect interventional constraints, the reconstructed structural causal models (SCMs) of the extended LPCMCI allow 84.6% of the time for the optimal prediction of the target variable. The implementation of interventional and observational causal discovery is modular, allowing causal constraints from other sources. The second part of this thesis investigates the question of regret minimizing control by simultaneously learning a causal model and planning actions through the causal model. The idea is that an agent to optimize a measured variable first learns the system's mechanics through observational causal discovery. The agent then intervenes on the most promising variable with randomized values allowing for the exploitation and generation of new interventional data. The agent then uses the interventional data to enhance the causal model further, allowing improved actions the next time. The extended LPCMCI can be favorable compared to the original LPCMCI algorithm. The numerical results show that detecting and using interventional constraints leads to reconstructed SCMs that allow 60.9% of the time for the optimal prediction of the target variable in contrast to the baseline of 53.6% when using the original LPCMCI algorithm. Furthermore, the induced average regret decreases from 1.2 when using the original LPCMCI algorithm to 1.0 when using the extended LPCMCI algorithm with interventional discovery.
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因果推断对于跨业务参与,医疗和政策制定等领域的数据驱动决策至关重要。然而,关于因果发现的研究已经与推理方法分开发展,从而阻止了两个领域方法的直接组合。在这项工作中,我们开发了深层端到端因果推理(DECI),这是一种基于流动的非线性添加噪声模型,该模型具有观察数据,并且可以执行因果发现和推理,包括有条件的平均治疗效果(CATE) )估计。我们提供了理论上的保证,即DECI可以根据标准因果发现假设恢复地面真实因果图。受应用影响的激励,我们将该模型扩展到具有缺失值的异质,混合型数据,从而允许连续和离散的治疗决策。我们的结果表明,与因果发现的相关基线相比,DECI的竞争性能和(c)在合成数据集和因果机器学习基准测试基准的一千多个实验中,跨数据类型和缺失水平进行了估计。
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考虑基于AI和ML的决策对这些新兴技术的安全和可接受的使用的决策的社会和道德后果至关重要。公平,特别是保证ML决定不会导致对个人或少数群体的歧视。使用因果关系,可以更好地实现和衡量可靠的公平/歧视,从而更好地实现了敏感属性(例如性别,种族,宗教等)之间的因果关系,仅仅是仅仅是关联,例如性别,种族,宗教等(例如,雇用工作,贷款授予等) )。然而,对因果关系解决公平性的最大障碍是因果模型的不可用(通常表示为因果图)。文献中现有的因果关系方法并不能解决此问题,并假设可获得因果模型。在本文中,我们没有做出这样的假设,并且我们回顾了从可观察数据中发现因果关系的主要算法。这项研究的重点是因果发现及其对公平性的影响。特别是,我们展示了不同的因果发现方法如何导致不同的因果模型,最重要的是,即使因果模型之间的轻微差异如何对公平/歧视结论产生重大影响。通过使用合成和标准公平基准数据集的经验分析来巩固这些结果。这项研究的主要目标是强调因果关系使用因果关系适当解决公平性的因果发现步骤的重要性。
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治疗效应估计的因果推理方法通常假设独立的实验单位。但是,由于实验单元可能会相互作用,因此这种假设通常值得怀疑。我们开发了增强的反可能性加权(AIPW),以估计和推断因果治疗对依赖观察数据的影响。我们的框架涵盖了网络中相互作用的单位引起的溢出效应的非常普遍的案例。我们使用插件机学习来估计无限维的滋扰成分,导致一致的治疗效应估计器以参数速率收敛,渐近地遵循高斯分布。
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Learning causal structure from observational data often assumes that we observe independent and identically distributed (i.\,i.\,d) data. The traditional approach aims to find a graphical representation that encodes the same set of conditional independence relationships as those present in the observed distribution. It is known that under i.\,i.\,d assumption, even with infinite data, there is a limit to how fine-grained a causal structure we can identify. To overcome this limitation, recent work has explored using data originating from different, related environments to learn richer causal structure. These approaches implicitly rely on the independent causal mechanisms (ICM) principle, which postulates that the mechanism giving rise to an effect given its causes and the mechanism which generates the causes do not inform or influence each other. Thus, components of the causal model can independently change from environment to environment. Despite its wide application in machine learning and causal inference, there is a lack of statistical formalization of the ICM principle and how it enables identification of richer causal structures from grouped data. Here we present new causal de Finetti theorems which offer a first statistical formalization of ICM principle and show how causal structure identification is possible from exchangeable data. Our work provides theoretical justification for a broad range of techniques leveraging multi-environment data to learn causal structure.
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研究了与隐藏变量有关的非循环图(DAG)相关的因果模型中因果效应的识别理论。然而,由于估计它们输出的识别功能的复杂性,因此未耗尽相应的算法。在这项工作中,我们弥合了识别和估算涉及单一治疗和单一结果的人口水平因果效应之间的差距。我们派生了基于功能的估计,在大类隐藏变量DAG中表现出对所识别的效果的双重稳健性,其中治疗满足简单的图形标准;该类包括模型,产生调整和前门功能作为特殊情况。我们还提供必要的和充分条件,其中隐藏变量DAG的统计模型是非分子饱和的,并且意味着对观察到的数据分布没有平等约束。此外,我们推导了一类重要的隐藏变量DAG,这意味着观察到观察到的数据分布等同于完全观察到的DAG等同于(最高的相等约束)。在这些DAG类中,我们推出了实现兴趣目标的半导体效率界限的估计估计值,该估计是治疗满足我们的图形标准的感兴趣的目标。最后,我们提供了一种完整的识别算法,可直接产生基于权重的估计策略,以了解隐藏可变因果模型中的任何可识别效果。
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在制定政策指南时,随机对照试验(RCT)代表了黄金标准。但是,RCT通常是狭窄的,并且缺乏更广泛的感兴趣人群的数据。这些人群中的因果效应通常是使用观察数据集估算的,这可能会遭受未观察到的混杂和选择偏见。考虑到一组观察估计(例如,来自多项研究),我们提出了一个试图拒绝偏见的观察性估计值的元偏值。我们使用验证效应,可以从RCT和观察数据中推断出的因果效应。在拒绝未通过此测试的估计器之后,我们对RCT中未观察到的亚组的外推性效应产生了保守的置信区间。假设至少一个观察估计量在验证和外推效果方面是渐近正常且一致的,我们为我们算法输出的间隔的覆盖率概率提供了保证。为了促进在跨数据集的因果效应运输的设置中,我们给出的条件下,即使使用灵活的机器学习方法用于估计滋扰参数,群体平均治疗效应的双重稳定估计值也是渐近的正常。我们说明了方法在半合成和现实世界数据集上的特性,并表明它与标准的荟萃分析技术相比。
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最近,已经提出了利用预测模型在不断变化的环境方面的不变性来推断响应变量的因果父母的子集的不变性。如果环境仅影响少数基本机制,则例如不变因果预测(ICP)确定的子集可能很小,甚至是空的。我们介绍了最小不变性的概念,并提出了不变的血统搜索(IAS)。在其人群版本中,IAS输出了一个仅包含响应祖先的集合,并且是ICP输出的超集。当应用于数据时,如果不变性的基础测试具有渐近水平和功率,则相应的保证会渐近。我们开发可扩展算法并在模拟和真实数据上执行实验。
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基于AI和机器学习的决策系统已在各种现实世界中都使用,包括医疗保健,执法,教育和金融。不再是牵强的,即设想一个未来,自治系统将推动整个业务决策,并且更广泛地支持大规模决策基础设施以解决社会最具挑战性的问题。当人类做出决定时,不公平和歧视的问题普遍存在,并且当使用几乎没有透明度,问责制和公平性的机器做出决定时(或可能会放大)。在本文中,我们介绍了\ textit {Causal公平分析}的框架,目的是填补此差距,即理解,建模,并可能解决决策设置中的公平性问题。我们方法的主要见解是将观察到数据中存在的差异的量化与基本且通常是未观察到的因果机制收集的因果机制的收集,这些机制首先会产生差异,挑战我们称之为因果公平的基本问题分析(FPCFA)。为了解决FPCFA,我们研究了分解差异和公平性的经验度量的问题,将这种变化归因于结构机制和人群的不同单位。我们的努力最终达到了公平地图,这是组织和解释文献中不同标准之间关系的首次系统尝试。最后,我们研究了进行因果公平分析并提出一本公平食谱的最低因果假设,该假设使数据科学家能够评估不同影响和不同治疗的存在。
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In this review, we discuss approaches for learning causal structure from data, also called causal discovery. In particular, we focus on approaches for learning directed acyclic graphs (DAGs) and various generalizations which allow for some variables to be unobserved in the available data. We devote special attention to two fundamental combinatorial aspects of causal structure learning. First, we discuss the structure of the search space over causal graphs. Second, we discuss the structure of equivalence classes over causal graphs, i.e., sets of graphs which represent what can be learned from observational data alone, and how these equivalence classes can be refined by adding interventional data.
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上下文的强盗和强化学习算法已成功用于各种交互式学习系统,例如在线广告,推荐系统和动态定价。但是,在高风险应用领域(例如医疗保健)中,它们尚未被广泛采用。原因之一可能是现有方法假定基本机制是静态的,因为它们不会在不同的环境上改变。但是,在许多现实世界中,这些机制可能会跨环境变化,这可能使静态环境假设无效。在本文中,考虑到离线上下文匪徒的框架,我们迈出了解决环境转变问题的一步。我们认为环境转移问题通过因果关系的角度,并提出了多种环境的背景匪徒,从而可以改变基本机制。我们采用因果关系文献的不变性概念,并介绍了政策不变性的概念。我们认为,仅当存在未观察到的变量时,政策不变性才有意义,并表明在这种情况下,保证在适当假设下跨环境概括最佳不变政策。我们的结果建立了因果关系,不变性和上下文土匪之间的具体联系。
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数据科学任务可以被视为了解数据的感觉或测试关于它的假设。从数据推断的结论可以极大地指导我们做出信息做出决定。大数据使我们能够与机器学习结合执行无数的预测任务,例如鉴定患有某种疾病的高风险患者并采取可预防措施。然而,医疗保健从业者不仅仅是仅仅预测的内容 - 它们也对输入特征和临床结果之间的原因关系感兴趣。了解这些关系将有助于医生治疗患者并有效降低风险。通常通过随机对照试验鉴定因果关系。当科学家和研究人员转向观察研究并试图吸引推论时,这种试验通常是不可行的。然而,观察性研究也可能受到选择和/或混淆偏差的影响,这可能导致错误的因果结论。在本章中,我们将尝试突出传统机器学习和统计方法中可能出现的一些缺点,以分析观察数据,特别是在医疗保健数据分析域中。我们将讨论因果化推理和方法,以发现医疗领域的观测研究原因。此外,我们将展示因果推断在解决某些普通机器学习问题等中的应用,例如缺少数据和模型可运输性。最后,我们将讨论将加强学习与因果关系相结合的可能性,作为反击偏见的一种方式。
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We consider the problem of recovering the causal structure underlying observations from different experimental conditions when the targets of the interventions in each experiment are unknown. We assume a linear structural causal model with additive Gaussian noise and consider interventions that perturb their targets while maintaining the causal relationships in the system. Different models may entail the same distributions, offering competing causal explanations for the given observations. We fully characterize this equivalence class and offer identifiability results, which we use to derive a greedy algorithm called GnIES to recover the equivalence class of the data-generating model without knowledge of the intervention targets. In addition, we develop a novel procedure to generate semi-synthetic data sets with known causal ground truth but distributions closely resembling those of a real data set of choice. We leverage this procedure and evaluate the performance of GnIES on synthetic, real, and semi-synthetic data sets. Despite the strong Gaussian distributional assumption, GnIES is robust to an array of model violations and competitive in recovering the causal structure in small- to large-sample settings. We provide, in the Python packages "gnies" and "sempler", implementations of GnIES and our semi-synthetic data generation procedure.
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在许多学科中,在大量解释变量中推断反应变量的直接因果父母的问题具有很高的实际意义。但是,建立的方法通常至少会随着解释变量的数量而呈指数级扩展,难以扩展到非线性关系,并且很难扩展到周期性数据。受{\ em Debiased}机器学习方法的启发,我们研究了一种单Vs.-the-Rest特征选择方法,以发现响应的直接因果父母。我们提出了一种用于纯观测数据的算法,同时还提供理论保证,包括可能在周期存在下的部分非线性关系的情况。由于它仅需要对每个变量进行一个估计,因此我们的方法甚至适用于大图。与既定方法相比,我们证明了显着改善。
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不观察到的混淆是观测数据的因果效应估计的主要障碍。仪器变量(IVS)广泛用于存在潜在混淆时的因果效应估计。利用标准IV方法,当给定的IV有效时,可以获得无偏估计,但标准IV的有效性要求是严格和不可能的。已经提出了通过调节一组观察变量(称为条件IV的调节装置)来放松标准IV的要求。然而,用于查找条件IV的调节集的标准需要完整的因果结构知识或指向的非循环图(DAG),其代表观察到和未观察的变量的因果关系。这使得无法发现直接从数据设置的调节。在本文中,通过利用潜在变量的因果推断中的最大祖先图(MAGS),我们提出了一种新型的MAG中的IV,祖先IV,并开发了支持给定祖传的调节装置的数据驱动的发现iv在mag。基于该理论,我们在MAG和观测数据中开发了一种与祖先IV的非偏见因果效应估计的算法。与现有IV方法相比,对合成和实际数据集的广泛实验表明了算法的性能。
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