早期检测改善了胰腺导管腺癌（PDAC）中的预后，但挑战，因为病变通常很小，并且在对比增强的计算断层扫描扫描（CE-CT）上定义很差。深度学习可以促进PDAC诊断，但是当前模型仍然无法识别小（<2cm）病变。在这项研究中，最先进的深度学习模型用于开发用于PDAC检测的自动框架，专注于小病变。另外，研究了整合周围解剖学的影响。 CE-CT来自119个病理验证的PDAC患者的群组和123名没有PDAC患者的队列用于训练NNUNET用于自动病变检测和分割（\ TEXTIT {NNUNET \ _t}）。训练了两种额外的鼻塞，以研究解剖学积分的影响：（1）分割胰腺和肿瘤（\ yryit {nnunet \ _tp}），（2）分割胰腺，肿瘤和多周围的解剖结构（\ textit {nnunet \_多发性硬化症}）。外部可公开的测试集用于比较三个网络的性能。 \ Textit {nnunet \ _ms}实现了最佳性能，在整个测试集的接收器操作特性曲线下的区域为0.91，肿瘤的0.88 <2cm，显示最先进的深度学习可以检测到小型PDAC和解剖信息的好处。

We demonstrate a proof-of-concept of a large language model conducting corporate lobbying related activities. We use an autoregressive large language model (OpenAI's text-davinci-003) to determine if proposed U.S. Congressional bills are relevant to specific public companies and provide explanations and confidence levels. For the bills the model deems as relevant, the model drafts a letter to the sponsor of the bill in an attempt to persuade the congressperson to make changes to the proposed legislation. We use hundreds of ground-truth labels of the relevance of a bill to a company to benchmark the performance of the model, which outperforms the baseline of predicting the most common outcome of irrelevance. However, we test the ability to determine the relevance of a bill with the previous OpenAI GPT-3 model (text-davinci-002), which was state-of-the-art on many language tasks until text-davinci-003 was released on November 28, 2022. The performance of text-davinci-002 is worse than simply always predicting that a bill is irrelevant to a company. These results suggest that, as large language models continue to improve core natural language understanding capabilities, performance on corporate lobbying related tasks will continue to improve. We then discuss why this could be problematic for societal-AI alignment.

Variational autoencoders model high-dimensional data by positing low-dimensional latent variables that are mapped through a flexible distribution parametrized by a neural network. Unfortunately, variational autoencoders often suffer from posterior collapse: the posterior of the latent variables is equal to its prior, rendering the variational autoencoder useless as a means to produce meaningful representations. Existing approaches to posterior collapse often attribute it to the use of neural networks or optimization issues due to variational approximation. In this paper, we consider posterior collapse as a problem of latent variable non-identifiability. We prove that the posterior collapses if and only if the latent variables are non-identifiable in the generative model. This fact implies that posterior collapse is not a phenomenon specific to the use of flexible distributions or approximate inference. Rather, it can occur in classical probabilistic models even with exact inference, which we also demonstrate. Based on these results, we propose a class of latent-identifiable variational autoencoders, deep generative models which enforce identifiability without sacrificing flexibility. This model class resolves the problem of latent variable non-identifiability by leveraging bijective Brenier maps and parameterizing them with input convex neural networks, without special variational inference objectives or optimization tricks. Across synthetic and real datasets, latent-identifiable variational autoencoders outperform existing methods in mitigating posterior collapse and providing meaningful representations of the data.

We introduce Argoverse 2 (AV2) - a collection of three datasets for perception and forecasting research in the self-driving domain. The annotated Sensor Dataset contains 1,000 sequences of multimodal data, encompassing high-resolution imagery from seven ring cameras, and two stereo cameras in addition to lidar point clouds, and 6-DOF map-aligned pose. Sequences contain 3D cuboid annotations for 26 object categories, all of which are sufficiently-sampled to support training and evaluation of 3D perception models. The Lidar Dataset contains 20,000 sequences of unlabeled lidar point clouds and map-aligned pose. This dataset is the largest ever collection of lidar sensor data and supports self-supervised learning and the emerging task of point cloud forecasting. Finally, the Motion Forecasting Dataset contains 250,000 scenarios mined for interesting and challenging interactions between the autonomous vehicle and other actors in each local scene. Models are tasked with the prediction of future motion for "scored actors" in each scenario and are provided with track histories that capture object location, heading, velocity, and category. In all three datasets, each scenario contains its own HD Map with 3D lane and crosswalk geometry - sourced from data captured in six distinct cities. We believe these datasets will support new and existing machine learning research problems in ways that existing datasets do not. All datasets are released under the CC BY-NC-SA 4.0 license.

In this paper we derive a PAC-Bayesian-Like error bound for a class of stochastic dynamical systems with inputs, namely, for linear time-invariant stochastic state-space models (stochastic LTI systems for short). This class of systems is widely used in control engineering and econometrics, in particular, they represent a special case of recurrent neural networks. In this paper we 1) formalize the learning problem for stochastic LTI systems with inputs, 2) derive a PAC-Bayesian-Like error bound for such systems, 3) discuss various consequences of this error bound.

We demonstrate how efficient autonomous drone swarms can be in detecting and tracking occluded targets in densely forested areas, such as lost people during search and rescue missions. Exploration and optimization of local viewing conditions, such as occlusion density and target view obliqueness, provide much faster and much more reliable results than previous, blind sampling strategies that are based on pre-defined waypoints. An adapted real-time particle swarm optimization and a new objective function are presented that are able to deal with dynamic and highly random through-foliage conditions. Synthetic aperture sensing is our fundamental sampling principle, and drone swarms are employed to approximate the optical signals of extremely wide and adaptable airborne lenses.

Generative AI has matured to a point where large-scale models can generate text that seems indistinguishable from human-written text and remarkably photorealistic images. Automatically measuring how close the distribution of generated data is to the target real data distribution is a key step in diagnosing existing models and developing better models. We present MAUVE, a family of comparison measures between pairs of distributions such as those encountered in the generative modeling of text or images. These scores are statistical summaries of divergence frontiers capturing two types of errors in generative modeling. We explore four approaches to statistically estimate these scores: vector quantization, non-parametric estimation, classifier-based estimation, and parametric Gaussian approximations. We provide statistical bounds for the vector quantization approach. Empirically, we find that the proposed scores paired with a range of $f$-divergences and statistical estimation methods can quantify the gaps between the distributions of human-written text and those of modern neural language models by correlating with human judgments and identifying known properties of the generated texts. We conclude the paper by demonstrating its applications to other AI domains and discussing practical recommendations.

Deep learning-based 3D human pose estimation performs best when trained on large amounts of labeled data, making combined learning from many datasets an important research direction. One obstacle to this endeavor are the different skeleton formats provided by different datasets, i.e., they do not label the same set of anatomical landmarks. There is little prior research on how to best supervise one model with such discrepant labels. We show that simply using separate output heads for different skeletons results in inconsistent depth estimates and insufficient information sharing across skeletons. As a remedy, we propose a novel affine-combining autoencoder (ACAE) method to perform dimensionality reduction on the number of landmarks. The discovered latent 3D points capture the redundancy among skeletons, enabling enhanced information sharing when used for consistency regularization. Our approach scales to an extreme multi-dataset regime, where we use 28 3D human pose datasets to supervise one model, which outperforms prior work on a range of benchmarks, including the challenging 3D Poses in the Wild (3DPW) dataset. Our code and models are available for research purposes.

Previous work has shown the potential of deep learning to predict renal obstruction using kidney ultrasound images. However, these image-based classifiers have been trained with the goal of single-visit inference in mind. We compare methods from video action recognition (i.e. convolutional pooling, LSTM, TSM) to adapt single-visit convolutional models to handle multiple visit inference. We demonstrate that incorporating images from a patient's past hospital visits provides only a small benefit for the prediction of obstructive hydronephrosis. Therefore, inclusion of prior ultrasounds is beneficial, but prediction based on the latest ultrasound is sufficient for patient risk stratification.

Traditionally, data analysis and theory have been viewed as separate disciplines, each feeding into fundamentally different types of models. Modern deep learning technology is beginning to unify these two disciplines and will produce a new class of predictively powerful space weather models that combine the physical insights gained by data and theory. We call on NASA to invest in the research and infrastructure necessary for the heliophysics' community to take advantage of these advances.