已经证明对比学习有效地对未标记数据的预训练图像模型有效，并且有希望的医学图像分类等任务的结果。在预训练期间使用配对文本和图像（例如放射性报告和图像）甚至进一步改善了结果。尽管如此，大多数现有方法将图像分类为下游任务，并且对于像语义分割或物体检测等本地化任务可能不是最佳的。因此，我们提出了从愿景和文本（Lovt）的局部代表学习，以实现我们最佳知识，这是针对本地化医学成像任务的第一种文本监督的预训练方法。我们的方法将实例级图像报告对比学习与图像区域和报告句子表示的局部对比学习结合起来。我们评估LOVT和常用的预培训方法，这些评估框架是由五个公共数据集的胸部X光上的18个本地化任务组成的新评估框架。虽然没有单一的最佳方法，但是，在18个研究的任务中，Lovt在11个中最佳地表现出优选的选择本地化任务的首选方法。

学习医学图像的视觉表示（例如X射线）是医学图像理解的核心，但由于人类注释的稀缺性，其进步已经阻止了它。现有的工作通常依赖于从成像网预处理传输的微调权重，由于图像特征截然不同，这是次优的，或者是从文本报告数据与医学图像配对的基于规则的标签提取，这是不准确的，难以推广。同时，最近的几项研究表明，从自然图像中学习的对比度学习令人兴奋，但由于它们的高层间相似性，我们发现这些方法对医学图像无济于事。我们提出了Concirt，这是一种替代的无监督策略，通过利用自然存在的配对描述性文本来学习医学视觉表示。我们通过两种模式之间的双向对比度目标对医学图像进行预处理编码的新方法是域，无关，不需要其他专家输入。我们通过将预处理的权重转移到4个医学图像分类任务和2个零射击检索任务中来测试交通，并证明它导致图像表示，在大多数设置中，它们都超过了强大的基线。值得注意的是，在所有4个分类任务中，我们的方法仅需要10 \％标记的培训数据与成像网初始化的对应物，以实现更好或可比的性能，从而证明了卓越的数据效率。

生物医学中的多模式数据遍布，例如放射学图像和报告。大规模解释这些数据对于改善临床护理和加速临床研究至关重要。与一般领域相比，具有复杂语义的生物医学文本在视觉建模中提出了其他挑战，并且先前的工作使用了缺乏特定领域语言理解的适应性模型不足。在本文中，我们表明，有原则的文本语义建模可以大大改善自我监督的视力 - 语言处理中的对比度学习。我们发布了一种实现最先进的语言模型，从而通过改进的词汇和新颖的语言预测客观的客观利用语义和话语特征在放射学报告中获得了自然语言推断。此外，我们提出了一种自我监督的联合视觉 - 语言方法，重点是更好的文本建模。它在广泛的公开基准上建立了新的最新结果，部分是通过利用我们新的特定领域的语言模型。我们释放了一个新的数据集，该数据集具有放射科医生的局部对齐短语接地注释，以促进生物医学视觉处理中复杂语义建模的研究。广泛的评估，包括在此新数据集中，表明我们的对比学习方法在文本语义建模的帮助下，尽管仅使用了全球对准目标，但在细分任务中的表现都优于细分任务中的先验方法。

Deep neural networks have been successfully adopted to diverse domains including pathology classification based on medical images. However, large-scale and high-quality data to train powerful neural networks are rare in the medical domain as the labeling must be done by qualified experts. Researchers recently tackled this problem with some success by taking advantage of models pre-trained on large-scale general domain data. Specifically, researchers took contrastive image-text encoders (e.g., CLIP) and fine-tuned it with chest X-ray images and paired reports to perform zero-shot pathology classification, thus completely removing the need for pathology-annotated images to train a classification model. Existing studies, however, fine-tuned the pre-trained model with the same contrastive learning objective, and failed to exploit the multi-labeled nature of medical image-report pairs. In this paper, we propose a new fine-tuning strategy based on sentence sampling and positive-pair loss relaxation for improving the downstream zero-shot pathology classification performance, which can be applied to any pre-trained contrastive image-text encoders. Our method consistently showed dramatically improved zero-shot pathology classification performance on four different chest X-ray datasets and 3 different pre-trained models (5.77% average AUROC increase). In particular, fine-tuning CLIP with our method showed much comparable or marginally outperformed to board-certified radiologists (0.619 vs 0.625 in F1 score and 0.530 vs 0.544 in MCC) in zero-shot classification of five prominent diseases from the CheXpert dataset.

We introduce Bootstrap Your Own Latent (BYOL), a new approach to self-supervised image representation learning. BYOL relies on two neural networks, referred to as online and target networks, that interact and learn from each other. From an augmented view of an image, we train the online network to predict the target network representation of the same image under a different augmented view. At the same time, we update the target network with a slow-moving average of the online network. While state-of-the art methods rely on negative pairs, BYOL achieves a new state of the art without them. BYOL reaches 74.3% top-1 classification accuracy on ImageNet using a linear evaluation with a ResNet-50 architecture and 79.6% with a larger ResNet. We show that BYOL performs on par or better than the current state of the art on both transfer and semi-supervised benchmarks. Our implementation and pretrained models are given on GitHub. 3 * Equal contribution; the order of first authors was randomly selected.

最先进的愿景和愿景和语言模型依靠大规模的Visio-linguisting预借鉴，以获得各种下游任务的良好性能。通常，这种模型通常是跨模态（对比）或多模态（具有早期融合）但不是两者;它们通常只针对特定的方式或任务。有希望的方向将是使用单一整体普遍模型，作为“基础”，目标是一次性的所有方式 - 真正的视觉和语言基础模型应该擅长视力任务，语言任务和交叉和多数模态视觉和语言任务。我们将Flava介绍在这样的模型中，并在跨越这些目标模式的广泛的35个任务上展示令人印象深刻的性能。

Image-text multimodal representation learning aligns data across modalities and enables important medical applications, e.g., image classification, visual grounding, and cross-modal retrieval. In this work, we establish a connection between multimodal representation learning and multiple instance learning. Based on this connection, we propose a generic framework for constructing permutation-invariant score functions with many existing multimodal representation learning approaches as special cases. Furthermore, we use the framework to derive a novel contrastive learning approach and demonstrate that our method achieves state-of-the-art results on a number of downstream tasks.

Computational pathology can lead to saving human lives, but models are annotation hungry and pathology images are notoriously expensive to annotate. Self-supervised learning has shown to be an effective method for utilizing unlabeled data, and its application to pathology could greatly benefit its downstream tasks. Yet, there are no principled studies that compare SSL methods and discuss how to adapt them for pathology. To address this need, we execute the largest-scale study of SSL pre-training on pathology image data, to date. Our study is conducted using 4 representative SSL methods on diverse downstream tasks. We establish that large-scale domain-aligned pre-training in pathology consistently out-performs ImageNet pre-training in standard SSL settings such as linear and fine-tuning evaluations, as well as in low-label regimes. Moreover, we propose a set of domain-specific techniques that we experimentally show leads to a performance boost. Lastly, for the first time, we apply SSL to the challenging task of nuclei instance segmentation and show large and consistent performance improvements under diverse settings.

通过自学学习的视觉表示是一项极具挑战性的任务，因为网络需要在没有监督提供的主动指导的情况下筛选出相关模式。这是通过大量数据增强，大规模数据集和过量量的计算来实现的。视频自我监督学习（SSL）面临着额外的挑战：视频数据集通常不如图像数据集那么大，计算是一个数量级，并且优化器所必须通过的伪造模式数量乘以几倍。因此，直接从视频数据中学习自我监督的表示可能会导致次优性能。为了解决这个问题，我们建议在视频表示学习框架中利用一个以自我或语言监督为基础的强大模型，并在不依赖视频标记的数据的情况下学习强大的空间和时间信息。为此，我们修改了典型的基于视频的SSL设计和目标，以鼓励视频编码器\ textit {subsume}基于图像模型的语义内容，该模型在通用域上训练。所提出的算法被证明可以更有效地学习（即在较小的时期和较小的批次中），并在单模式SSL方法中对标准下游任务进行了新的最新性能。

本文提出了一种对比调整，这是一种简单的方法，采用对比训练来对准图像和文本模型，同时仍然利用他们的预训练。在我们的实证研究中，我们发现，锁定的预训练图像模型与解锁文本模型最佳。我们调用这种对比调整“锁定图像文本调整”（LIT TOONING）的实例，该实例仅教导文本模型，从预先训练的图像模型中读出了良好的表示新任务。亮度调谐模型将零拍摄传输到新视觉任务的能力提高，例如图像分类或检索。建议的亮度调整是广泛适用的;它可以使用三种不同的图像文本数据集可靠地使用多种预训练方法（监督和无监督）和多种架构（Reset，Vision变换器和MLP-MILLER）。利用基于变压器的预训练VIT-G / 14型号，LIT调谐模型在想象网测试集中实现了84.5％的零射频传输精度，并且在充满挑战的分发ObjectNet测试集中实现了81.1％。

Contrastive learning has become a key component of self-supervised learning approaches for computer vision. By learning to embed two augmented versions of the same image close to each other and to push the embeddings of different images apart, one can train highly transferable visual representations. As revealed by recent studies, heavy data augmentation and large sets of negatives are both crucial in learning such representations. At the same time, data mixing strategies, either at the image or the feature level, improve both supervised and semi-supervised learning by synthesizing novel examples, forcing networks to learn more robust features. In this paper, we argue that an important aspect of contrastive learning, i.e. the effect of hard negatives, has so far been neglected. To get more meaningful negative samples, current top contrastive self-supervised learning approaches either substantially increase the batch sizes, or keep very large memory banks; increasing memory requirements, however, leads to diminishing returns in terms of performance. We therefore start by delving deeper into a top-performing framework and show evidence that harder negatives are needed to facilitate better and faster learning. Based on these observations, and motivated by the success of data mixing, we propose hard negative mixing strategies at the feature level, that can be computed on-the-fly with a minimal computational overhead. We exhaustively ablate our approach on linear classification, object detection, and instance segmentation and show that employing our hard negative mixing procedure improves the quality of visual representations learned by a state-of-the-art self-supervised learning method.Project page: https://europe.naverlabs.com/mochi 34th Conference on Neural Information Processing Systems (NeurIPS 2020),

在过去的几年中，基于自我注意力的变压器模型一直在主导许多计算机视觉任务。它们的出色模型质量在很大程度上取决于标记过多的图像数据集。为了减少对大型标记数据集的依赖，基于重建的掩盖自动编码器正在获得流行，这些自动编码器从未标记的图像中学习了高质量的可转移表示形式。出于同样的目的，最近弱监督的图像预处理方法探索了图像随附的文本字幕的语言监督。在这项工作中，我们提出了对语言辅助代表的预读图像，称为米兰。我们的预处理目标不是预测原始像素或低级别的特征，而是用使用字幕监督获得的大量语义信号来重建图像特征。此外，为了适应我们的重建目标，我们提出了更有效的促使解码器体系结构和语义意识到的掩码采样机制，从而进一步推进了预告片模型的传输性能。实验结果表明，米兰的精度比以前的工作更高。当掩盖的自动编码器在ImagEnet-1K数据集上进行了预估计并以224x224的输入分辨率进行了填充时，米兰在VITB/16上的前1位准确性达到了85.4％，使以前的先前最先前的艺术品达到1％。在下游的语义分割任务中，米兰在ADE20K数据集上使用VIT-B/16骨架达到52.7 MIOU，表现优于先前的蒙版预读结果4分。

监督的深度学习模型取决于大量标记的数据。不幸的是，收集和注释包含所需更改的零花态样本是耗时和劳动密集型的。从预训练模型中转移学习可有效减轻遥感（RS）变化检测（CD）中标签不足。我们探索在预训练期间使用语义信息的使用。不同于传统的监督预训练，该预训练从图像到标签，我们将语义监督纳入了自我监督的学习（SSL）框架中。通常，多个感兴趣的对象（例如，建筑物）以未经切割的RS图像分布在各个位置。我们没有通过全局池操纵图像级表示，而是在每个像素嵌入式上引入点级监督以学习空间敏感的特征，从而使下游密集的CD受益。为了实现这一目标，我们通过使用语义掩码在视图之间的重叠区域上通过类平衡的采样获得了多个点。我们学会了一个嵌入式空间，将背景和前景点分开，并将视图之间的空间对齐点齐聚在一起。我们的直觉是导致的语义歧视性表示与无关的变化不变（照明和无关紧要的土地覆盖）可能有助于改变识别。我们在RS社区中免费提供大规模的图像面罩，用于预训练。在三个CD数据集上进行的大量实验验证了我们方法的有效性。我们的表现明显优于Imagenet预训练，内域监督和几种SSL方法。经验结果表明我们的预训练提高了CD模型的概括和数据效率。值得注意的是，我们使用20％的培训数据获得了比基线（随机初始化）使用100％数据获得竞争结果。我们的代码可用。

人工智能（AI）的基本目标是模仿人类的核心认知活动。尽管在AI研究中取得了巨大的成功，但大多数现有方法仅具有单认知能力。为了克服这一局限性并迈出了朝着人工通用智能（AGI）迈出的坚实一步，我们开发了一个通过庞大的多模式数据进行预训练的基础模型，可以快速适应各种下游认知任务。为了实现这一目标，我们建议通过从Internet上拖延的语义相关数据进行自我监督的学习来预先培训我们的基础模型，并表明可以在各种下游任务上获得有希望的结果。特别是，使用开发的模型解剖工具，我们证明了我们的基础模型现在拥有强大的想象力。我们认为，我们的工作从我们的“弱或狭窄AI”的常见实践到“强或广泛的AI”迈出了转变的迈向AGI。

作为人类已知的最直观的界面之一，自然语言有可能调解许多涉及人类计算机互动的任务，尤其是在音乐信息检索等以应用程序为中心的领域。在这项工作中，我们探索了跨模式学习，以试图在音乐领域弥合音频和语言。为此，我们提出了Muscall，这是音乐对比的音频学习框架。我们的方法由双重编码架构组成，该体系结构了解音乐音频和描述性句子对之间的对齐方式，生成可用于文本到原告和音频到文本检索的多模式嵌入。多亏了这个属性，肌肉几乎可以转移到任何可以作为基于文本检索的任务转移到任何任务。我们的实验表明，我们的方法在检索音频时的性能要比基线要好得多，该音频与文本描述匹配，相反，与音频查询匹配的文本。我们还证明，我们的模型的多模式对齐能力可以成功扩展到零摄像转移方案，用于流派分类和在两个公共数据集上自动标记。

State-of-the-art computer vision systems are trained to predict a fixed set of predetermined object categories. This restricted form of supervision limits their generality and usability since additional labeled data is needed to specify any other visual concept. Learning directly from raw text about images is a promising alternative which leverages a much broader source of supervision. We demonstrate that the simple pre-training task of predicting which caption goes with which image is an efficient and scalable way to learn SOTA image representations from scratch on a dataset of 400 million (image, text) pairs collected from the internet. After pre-training, natural language is used to reference learned visual concepts (or describe new ones) enabling zero-shot transfer of the model to downstream tasks. We study the performance of this approach by benchmarking on over 30 different existing computer vision datasets, spanning tasks such as OCR, action recognition in videos, geo-localization, and many types of fine-grained object classification. The model transfers non-trivially to most tasks and is often competitive with a fully supervised baseline without the need for any dataset specific training. For instance, we match the accuracy of the original ResNet-50 on ImageNet zero-shot without needing to use any of the 1.28 million training examples it was trained on. We release our code and pre-trained model weights at https://github.com/OpenAI/CLIP.

Pre-trained representations are becoming crucial for many NLP and perception tasks. While representation learning in NLP has transitioned to training on raw text without human annotations, visual and vision-language representations still rely heavily on curated training datasets that are expensive or require expert knowledge. For vision applications, representations are mostly learned using datasets with explicit class labels such as Ima-geNet or OpenImages. For vision-language, popular datasets like Conceptual Captions, MSCOCO, or CLIP all involve a non-trivial data collection (and cleaning) process. This costly curation process limits the size of datasets and hence hinders the scaling of trained models. In this paper, we leverage a noisy dataset of over one billion image alt-text pairs, obtained without expensive filtering or post-processing steps in the Conceptual Captions dataset. A simple dual-encoder architecture learns to align visual and language representations of the image and text pairs using a contrastive loss. We show that the scale of our corpus can make up for its noise and leads to state-of-the-art representations even with such a simple learning scheme. Our visual representation achieves strong performance when transferred to classification tasks such as ImageNet and VTAB. The aligned visual and language representations enables zero-shot image classification and also set new state-of-the-art results on Flickr30K and MSCOCO image-text retrieval benchmarks, even when compared with more sophisticated crossattention models. The representations also enable cross-modality search with complex text and text + image queries.

Joint image-text embedding is the bedrock for most Visionand-Language (V+L) tasks, where multimodality inputs are simultaneously processed for joint visual and textual understanding. In this paper, we introduce UNITER, a UNiversal Image-TExt Representation, learned through large-scale pre-training over four image-text datasets (COCO, Visual Genome, Conceptual Captions, and SBU Captions), which can power heterogeneous downstream V+L tasks with joint multimodal embeddings. We design four pre-training tasks: Masked Language Modeling (MLM), Masked Region Modeling (MRM, with three variants), Image-Text Matching (ITM), and Word-Region Alignment (WRA). Different from previous work that applies joint random masking to both modalities, we use conditional masking on pre-training tasks (i.e., masked language/region modeling is conditioned on full observation of image/text). In addition to ITM for global image-text alignment, we also propose WRA via the use of Optimal Transport (OT) to explicitly encourage finegrained alignment between words and image regions during pre-training. Comprehensive analysis shows that both conditional masking and OTbased WRA contribute to better pre-training. We also conduct a thorough ablation study to find an optimal combination of pre-training tasks. Extensive experiments show that UNITER achieves new state of the art across six V+L tasks (over nine datasets), including Visual Question

This paper presents SimCLR: a simple framework for contrastive learning of visual representations. We simplify recently proposed contrastive selfsupervised learning algorithms without requiring specialized architectures or a memory bank. In order to understand what enables the contrastive prediction tasks to learn useful representations, we systematically study the major components of our framework. We show that (1) composition of data augmentations plays a critical role in defining effective predictive tasks, (2) introducing a learnable nonlinear transformation between the representation and the contrastive loss substantially improves the quality of the learned representations, and (3) contrastive learning benefits from larger batch sizes and more training steps compared to supervised learning. By combining these findings, we are able to considerably outperform previous methods for self-supervised and semi-supervised learning on ImageNet. A linear classifier trained on self-supervised representations learned by Sim-CLR achieves 76.5% top-1 accuracy, which is a 7% relative improvement over previous state-ofthe-art, matching the performance of a supervised ResNet-50. When fine-tuned on only 1% of the labels, we achieve 85.8% top-5 accuracy, outperforming AlexNet with 100× fewer labels. 1