We present Muse, a text-to-image Transformer model that achieves state-of-the-art image generation performance while being significantly more efficient than diffusion or autoregressive models. Muse is trained on a masked modeling task in discrete token space: given the text embedding extracted from a pre-trained large language model (LLM), Muse is trained to predict randomly masked image tokens. Compared to pixel-space diffusion models, such as Imagen and DALL-E 2, Muse is significantly more efficient due to the use of discrete tokens and requiring fewer sampling iterations; compared to autoregressive models, such as Parti, Muse is more efficient due to the use of parallel decoding. The use of a pre-trained LLM enables fine-grained language understanding, translating to high-fidelity image generation and the understanding of visual concepts such as objects, their spatial relationships, pose, cardinality etc. Our 900M parameter model achieves a new SOTA on CC3M, with an FID score of 6.06. The Muse 3B parameter model achieves an FID of 7.88 on zero-shot COCO evaluation, along with a CLIP score of 0.32. Muse also directly enables a number of image editing applications without the need to fine-tune or invert the model: inpainting, outpainting, and mask-free editing. More results are available at https://muse-model.github.io

Objective: We aim to develop an open-source natural language processing (NLP) package, SODA (i.e., SOcial DeterminAnts), with pre-trained transformer models to extract social determinants of health (SDoH) for cancer patients, examine the generalizability of SODA to a new disease domain (i.e., opioid use), and evaluate the extraction rate of SDoH using cancer populations. Methods: We identified SDoH categories and attributes and developed an SDoH corpus using clinical notes from a general cancer cohort. We compared four transformer-based NLP models to extract SDoH, examined the generalizability of NLP models to a cohort of patients prescribed with opioids, and explored customization strategies to improve performance. We applied the best NLP model to extract 19 categories of SDoH from the breast (n=7,971), lung (n=11,804), and colorectal cancer (n=6,240) cohorts. Results and Conclusion: We developed a corpus of 629 cancer patients notes with annotations of 13,193 SDoH concepts/attributes from 19 categories of SDoH. The Bidirectional Encoder Representations from Transformers (BERT) model achieved the best strict/lenient F1 scores of 0.9216 and 0.9441 for SDoH concept extraction, 0.9617 and 0.9626 for linking attributes to SDoH concepts. Fine-tuning the NLP models using new annotations from opioid use patients improved the strict/lenient F1 scores from 0.8172/0.8502 to 0.8312/0.8679. The extraction rates among 19 categories of SDoH varied greatly, where 10 SDoH could be extracted from >70% of cancer patients, but 9 SDoH had a low extraction rate (<70% of cancer patients). The SODA package with pre-trained transformer models is publicly available at https://github.com/uf-hobiinformatics-lab/SDoH_SODA.

As large language models (LLMs) grow larger and more sophisticated, assessing their "reasoning" capabilities in natural language grows more challenging. Recent question answering (QA) benchmarks that attempt to assess reasoning are often limited by a narrow scope of covered situations and subject matters. We introduce WikiWhy, a QA dataset built around a novel auxiliary task: explaining why an answer is true in natural language. WikiWhy contains over 9,000 "why" question-answer-rationale triples, grounded on Wikipedia facts across a diverse set of topics. Each rationale is a set of supporting statements connecting the question to the answer. WikiWhy serves as a benchmark for the reasoning capabilities of LLMs because it demands rigorous explicit rationales for each answer to demonstrate the acquisition of implicit commonsense knowledge, which is unlikely to be easily memorized. GPT-3 baselines achieve only 38.7% human-evaluated correctness in the end-to-end answer & explain condition, leaving significant room for future improvements.

We present the Habitat-Matterport 3D Semantics (HM3DSEM) dataset. HM3DSEM is the largest dataset of 3D real-world spaces with densely annotated semantics that is currently available to the academic community. It consists of 142,646 object instance annotations across 216 3D spaces and 3,100 rooms within those spaces. The scale, quality, and diversity of object annotations far exceed those of prior datasets. A key difference setting apart HM3DSEM from other datasets is the use of texture information to annotate pixel-accurate object boundaries. We demonstrate the effectiveness of HM3DSEM dataset for the Object Goal Navigation task using different methods. Policies trained using HM3DSEM perform outperform those trained on prior datasets. Introduction of HM3DSEM in the Habitat ObjectNav Challenge lead to an increase in participation from 400 submissions in 2021 to 1022 submissions in 2022.

标准人工神经网络（ANNS）使用无内存非线性激活的总和产生或多功能节点操作。这些神经网络已知具有通用功能近似功能。先前提出的形态学感知器使用Max-sum，代替总产量，节点处理，并具有有希望的电路实现属性。在本文中，我们表明这些Max-SUM ANN没有通用近似功能。此外，我们考虑了形态学上的签名签名的最大和最大 - 明星和最大 - 星级概括，并表明这些变体也没有通用的近似能力。我们将这些变化与对数数字系统（LNS）的实现进行对比，这些变化也避免了乘法，但确实具有通用的近似功能。

肺癌往往在晚期检测到，导致患者死亡率高。因此，最近的研究集中在早期疾病检测上。肺癌通常首先出现在气道壁的支气管上皮内发生的病变。支气管镜检查是有效无创支气化病变检测的选择程序。特别是，自身荧光支气管镜检查（AFB）区分了正常组织和患病组织的自荧光特性，在AFB视频帧中，病变在AFB视频帧中显得红棕色，而正常组织则为绿色。由于最近的研究表明AFB具有高病变敏感性的能力，因此在标准的支气管镜呼吸道考试中，它已成为一种潜在的关键方法，用于早期肺癌检测。不幸的是，对AFB视频的手动检查非常乏味且容易出错，而有限的努力已花费在可能更健壮的自动AFB病变检测和细分方面。我们提出了一个实时的深度学习体系结构ESFPNET，用于从AFB视频流中对支气管病变的强大检测和分割。该体系结构具有编码器结构，该结构可利用预审计的混合变压器（MIT）编码器和阶段特征金字塔（ESFP）解码器结构。来自肺癌患者气道考试的AFB视频的结果表明，我们的方法分别给出了平均骰子指数和0.782和0.658的IOU值，而处理吞吐量为27帧/秒。这些值优于使用混合变压器或基于CNN的编码器的其他竞争体系结构获得的结果。此外，ETIS-LaribpolypDB数据集的出色性能证明了其对其他域的潜在适用性。

语言模型既展示了定量的改进，又展示了新的定性功能，随着规模的增加。尽管它们具有潜在的变革性影响，但这些新能力的特征却很差。为了为未来的研究提供信息，为破坏性的新模型能力做准备，并改善社会有害的效果，至关重要的是，我们必须了解目前和近乎未来的能力和语言模型的局限性。为了应对这一挑战，我们介绍了超越模仿游戏基准（Big Bench）。 Big Bench目前由204个任务组成，由132家机构的442位作者贡献。任务主题是多样的，从语言学，儿童发展，数学，常识性推理，生物学，物理学，社会偏见，软件开发等等。 Big-Bench专注于被认为超出当前语言模型的功能的任务。我们评估了OpenAI的GPT型号，Google内部密集变压器体系结构和大型基础上的开关稀疏变压器的行为，跨越了数百万到数十亿个参数。此外，一个人类专家评估者团队执行了所有任务，以提供强大的基准。研究结果包括：模型性能和校准都随规模改善，但绝对的术语（以及与评估者的性能相比）；在模型类中的性能非常相似，尽管带有稀疏性。逐渐和预测的任务通常涉及大量知识或记忆成分，而在临界规模上表现出“突破性”行为的任务通常涉及多个步骤或组成部分或脆性指标；社交偏见通常会随着含糊不清的环境而随着规模而增加，但这可以通过提示来改善。

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for medical AI systems utilizing clinical narratives. However, there are few clinical language models, the largest of which trained in the clinical domain is comparatively small at 110 million parameters (compared with billions of parameters in the general domain). It is not clear how large clinical language models with billions of parameters can help medical AI systems utilize unstructured EHRs. In this study, we develop from scratch a large clinical language model - GatorTron - using >90 billion words of text (including >82 billion words of de-identified clinical text) and systematically evaluate it on 5 clinical NLP tasks including clinical concept extraction, medical relation extraction, semantic textual similarity, natural language inference (NLI), and medical question answering (MQA). We examine how (1) scaling up the number of parameters and (2) scaling up the size of the training data could benefit these NLP tasks. GatorTron models scale up the clinical language model from 110 million to 8.9 billion parameters and improve 5 clinical NLP tasks (e.g., 9.6% and 9.5% improvement in accuracy for NLI and MQA), which can be applied to medical AI systems to improve healthcare delivery. The GatorTron models are publicly available at: https://catalog.ngc.nvidia.com/orgs/nvidia/teams/clara/models/gatortron_og.

我们使用条件扩散模型介绍调色板，这是一种简单而一般的框架，可用于图像到图像到图像转换。在四个具有挑战性的图像到图像转换任务（着色，染色，un折叠和JPEG减压），调色板优于强大的GaN和回归基线，并建立了新的最新状态。这是在没有特定于任务特定的超参数调整，架构定制或任何辅助损耗的情况下实现的，展示了理想的一般性和灵活性。我们揭示了使用$ l_2 $与vs. $ l_1 $损失在样本多样性上的越来越多的影响，并通过经验架构研究表明自我关注的重要性。重要的是，我们倡导基于想象项目的统一评估协议，并报告包括预先训练的Reset-50的FID，成立得分，分类准确度的多个样本质量评分，以及针对各种基线的参考图像的感知距离。我们预计这一标准化评估协议在推进图像到图像翻译研究方面发挥着关键作用。最后，我们表明，在3个任务（着色，染色，JPEG减压）上培训的单个通用调色板模型也表现或优于特定于任务专家的专家对应物。

The recent increase in public and academic interest in preserving biodiversity has led to the growth of the field of conservation technology. This field involves designing and constructing tools that utilize technology to aid in the conservation of wildlife. In this article, we will use case studies to demonstrate the importance of designing conservation tools with human-wildlife interaction in mind and provide a framework for creating successful tools. These case studies include a range of complexities, from simple cat collars to machine learning and game theory methodologies. Our goal is to introduce and inform current and future researchers in the field of conservation technology and provide references for educating the next generation of conservation technologists. Conservation technology not only has the potential to benefit biodiversity but also has broader impacts on fields such as sustainability and environmental protection. By using innovative technologies to address conservation challenges, we can find more effective and efficient solutions to protect and preserve our planet's resources.