背景：基于学习的深度颈部淋巴结水平（HN_LNL）自动纤维与放射疗法研究和临床治疗计划具有很高的相关性，但在学术文献中仍被研究过。方法：使用35个规划CTS的专家划分的队列用于培训NNU-NEN 3D FULLES/2D-ENEBLEN模型，用于自动分片20不同的HN_LNL。验证是在独立的测试集（n = 20）中进行的。在一项完全盲目的评估中，3位临床专家在与专家创建的轮廓的正面比较中对深度学习自动分类的质量进行了评价。对于10个病例的亚组，将观察者内的变异性与深度学习自动分量性能进行了比较。研究了Autocontour与CT片平面方向的一致性对几何精度和专家评级的影响。结果：与专家创建的轮廓相比，对CT SLICE平面调整的深度学习分割的平均盲目专家评级明显好得多（81.0 vs. 79.6，p <0.001），但没有切片平面的深度学习段的评分明显差。专家创建的轮廓（77.2 vs. 79.6，p <0.001）。深度学习分割的几何准确性与观察者内变异性（平均骰子，0.78 vs. 0.77，p = 0.064）的几何准确性无关，并且在提高水平之间的准确性方面差异（p <0.001）。与CT切片平面方向一致性的临床意义未由几何精度指标（骰子，0.78 vs. 0.78 vs. 0.78，p = 0.572）结论：我们表明可以将NNU-NENE-NET 3D-FULLRES/2D-ENEMELBEND用于HN_LNL高度准确的自动限制仅使用有限的培训数据集，该数据集非常适合在研究环境中在HN_LNL的大规模标准化自动限制。几何准确度指标只是盲人专家评级的不完善的替代品。

Furigana是日语写作中使用的发音笔记。能够检测到这些可以帮助提高光学特征识别（OCR）性能，或通过正确显示Furigana来制作日本书面媒体的更准确的数字副本。该项目的重点是在日本书籍和漫画中检测Furigana。尽管已经研究了日本文本的检测，但目前尚无提议检测Furigana的方法。我们构建了一个包含日本书面媒体和Furigana注释的新数据集。我们建议对此类数据的评估度量，该度量与对象检测中使用的评估协议类似，除非它允许对象组通过一个注释标记。我们提出了一种基于数学形态和连接组件分析的Furigana检测方法。我们评估数据集的检测，并比较文本提取的不同方法。我们还分别评估了不同类型的图像，例如书籍和漫画，并讨论每种图像的挑战。所提出的方法在数据集上达到76 \％的F1得分。该方法在常规书籍上表现良好，但在漫画和不规则格式的书籍上的表现较少。最后，我们证明所提出的方法可以在漫画109数据集上提高OCR的性能5 \％。源代码可通过\ texttt {\ url {https://github.com/nikolajkb/furiganadetection}}}

迄今为止，迄今为止，众所周知，对广泛的互补临床相关任务进行了全面比较了医学图像登记方法。这限制了采用研究进展，以防止竞争方法的公平基准。在过去五年内已经探讨了许多新的学习方法，但优化，建筑或度量战略的问题非常适合仍然是开放的。 Learn2reg涵盖了广泛的解剖学：脑，腹部和胸部，方式：超声波，CT，MRI，群体：患者内部和患者内部和监督水平。我们为3D注册的培训和验证建立了较低的入境障碍，这帮助我们从20多个独特的团队中汇编了65多个单独的方法提交的结果。我们的互补度量集，包括稳健性，准确性，合理性和速度，使得能够独特地位了解当前的医学图像登记现状。进一步分析监督问题的转移性，偏见和重要性，主要是基于深度学习的方法的优越性，并将新的研究方向开放到利用GPU加速的常规优化的混合方法。

移动对象检测和分割是自主驱动管道中的基本任务。检测和隔离车辆周围环境的静态和移动部件在路径规划和定位任务中特别关键。本文提出了一种新的实时架构，用于光检测和测距（LIDAR）数据的运动分割。我们在2D鸟瞰图（BEV）表示中使用两个连续扫描的LIDAR数据（BEV）表示，以将像素明智的分类执行为静态或移动。此外，我们提出了一种新的数据增强技术，以减少静态和移动物体之间的显着类别不平衡。我们通过用切割和粘贴静电车辆人工合成移动物体来实现这一点。我们在常用的汽车嵌入式平台上展示了​​8毫秒的低延迟，即Nvidia Jetson Xavier。据我们所知，这是第一个直接在Lidar Bev空间中执行运动细分的工作。我们为具有挑战性的Semantickitti数据集提供定量结果，HTTPS://youtu.be/2AJ-CL8B0LI提供定性结果。

Diversity Searcher is a tool originally developed to help analyse diversity in news media texts. It relies on a form of automated content analysis and thus rests on prior assumptions and depends on certain design choices related to diversity and fairness. One such design choice is the external knowledge source(s) used. In this article, we discuss implications that these sources can have on the results of content analysis. We compare two data sources that Diversity Searcher has worked with - DBpedia and Wikidata - with respect to their ontological coverage and diversity, and describe implications for the resulting analyses of text corpora. We describe a case study of the relative over- or under-representation of Belgian political parties between 1990 and 2020 in the English-language DBpedia, the Dutch-language DBpedia, and Wikidata, and highlight the many decisions needed with regard to the design of this data analysis and the assumptions behind it, as well as implications from the results. In particular, we came across a staggering over-representation of the political right in the English-language DBpedia.

Artificial intelligence(AI) systems based on deep neural networks (DNNs) and machine learning (ML) algorithms are increasingly used to solve critical problems in bioinformatics, biomedical informatics, and precision medicine. However, complex DNN or ML models that are unavoidably opaque and perceived as black-box methods, may not be able to explain why and how they make certain decisions. Such black-box models are difficult to comprehend not only for targeted users and decision-makers but also for AI developers. Besides, in sensitive areas like healthcare, explainability and accountability are not only desirable properties of AI but also legal requirements -- especially when AI may have significant impacts on human lives. Explainable artificial intelligence (XAI) is an emerging field that aims to mitigate the opaqueness of black-box models and make it possible to interpret how AI systems make their decisions with transparency. An interpretable ML model can explain how it makes predictions and which factors affect the model's outcomes. The majority of state-of-the-art interpretable ML methods have been developed in a domain-agnostic way and originate from computer vision, automated reasoning, or even statistics. Many of these methods cannot be directly applied to bioinformatics problems, without prior customization, extension, and domain adoption. In this paper, we discuss the importance of explainability with a focus on bioinformatics. We analyse and comprehensively overview of model-specific and model-agnostic interpretable ML methods and tools. Via several case studies covering bioimaging, cancer genomics, and biomedical text mining, we show how bioinformatics research could benefit from XAI methods and how they could help improve decision fairness.

Kernel machines have sustained continuous progress in the field of quantum chemistry. In particular, they have proven to be successful in the low-data regime of force field reconstruction. This is because many physical invariances and symmetries can be incorporated into the kernel function to compensate for much larger datasets. So far, the scalability of this approach has however been hindered by its cubical runtime in the number of training points. While it is known, that iterative Krylov subspace solvers can overcome these burdens, they crucially rely on effective preconditioners, which are elusive in practice. Practical preconditioners need to be computationally efficient and numerically robust at the same time. Here, we consider the broad class of Nystr\"om-type methods to construct preconditioners based on successively more sophisticated low-rank approximations of the original kernel matrix, each of which provides a different set of computational trade-offs. All considered methods estimate the relevant subspace spanned by the kernel matrix columns using different strategies to identify a representative set of inducing points. Our comprehensive study covers the full spectrum of approaches, starting from naive random sampling to leverage score estimates and incomplete Cholesky factorizations, up to exact SVD decompositions.

We present an automatic method for annotating images of indoor scenes with the CAD models of the objects by relying on RGB-D scans. Through a visual evaluation by 3D experts, we show that our method retrieves annotations that are at least as accurate as manual annotations, and can thus be used as ground truth without the burden of manually annotating 3D data. We do this using an analysis-by-synthesis approach, which compares renderings of the CAD models with the captured scene. We introduce a 'cloning procedure' that identifies objects that have the same geometry, to annotate these objects with the same CAD models. This allows us to obtain complete annotations for the ScanNet dataset and the recent ARKitScenes dataset.

Objective: Imbalances of the electrolyte concentration levels in the body can lead to catastrophic consequences, but accurate and accessible measurements could improve patient outcomes. While blood tests provide accurate measurements, they are invasive and the laboratory analysis can be slow or inaccessible. In contrast, an electrocardiogram (ECG) is a widely adopted tool which is quick and simple to acquire. However, the problem of estimating continuous electrolyte concentrations directly from ECGs is not well-studied. We therefore investigate if regression methods can be used for accurate ECG-based prediction of electrolyte concentrations. Methods: We explore the use of deep neural networks (DNNs) for this task. We analyze the regression performance across four electrolytes, utilizing a novel dataset containing over 290000 ECGs. For improved understanding, we also study the full spectrum from continuous predictions to binary classification of extreme concentration levels. To enhance clinical usefulness, we finally extend to a probabilistic regression approach and evaluate different uncertainty estimates. Results: We find that the performance varies significantly between different electrolytes, which is clinically justified in the interplay of electrolytes and their manifestation in the ECG. We also compare the regression accuracy with that of traditional machine learning models, demonstrating superior performance of DNNs. Conclusion: Discretization can lead to good classification performance, but does not help solve the original problem of predicting continuous concentration levels. While probabilistic regression demonstrates potential practical usefulness, the uncertainty estimates are not particularly well-calibrated. Significance: Our study is a first step towards accurate and reliable ECG-based prediction of electrolyte concentration levels.

Earthquakes, fire, and floods often cause structural collapses of buildings. The inspection of damaged buildings poses a high risk for emergency forces or is even impossible, though. We present three recent selected missions of the Robotics Task Force of the German Rescue Robotics Center, where both ground and aerial robots were used to explore destroyed buildings. We describe and reflect the missions as well as the lessons learned that have resulted from them. In order to make robots from research laboratories fit for real operations, realistic test environments were set up for outdoor and indoor use and tested in regular exercises by researchers and emergency forces. Based on this experience, the robots and their control software were significantly improved. Furthermore, top teams of researchers and first responders were formed, each with realistic assessments of the operational and practical suitability of robotic systems.