Machine-Learned Likelihoods (MLL) is a method that, by combining modern machine-learning classification techniques with likelihood-based inference tests, allows to estimate the experimental sensitivity of high-dimensional data sets. We extend the MLL method by including the exclusion hypothesis tests and show that the addition of Kernel Density Estimators avoids the need to bin the classifier output in order to extract the resulting one-dimensional signal and background probability density functions. We first test our method on toy models generated with multivariate Gaussian distributions, where the true probability distribution functions are known. We then apply it to a case of interest in the search for new physics at the HL-LHC, in which a $Z^\prime$ boson decays into lepton pairs, comparing the performance of our method for estimating 95\% CL exclusion limits to the results obtained applying a binned likelihood to the machine-learning classifier output.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

Objective: Accurate visual classification of bladder tissue during Trans-Urethral Resection of Bladder Tumor (TURBT) procedures is essential to improve early cancer diagnosis and treatment. During TURBT interventions, White Light Imaging (WLI) and Narrow Band Imaging (NBI) techniques are used for lesion detection. Each imaging technique provides diverse visual information that allows clinicians to identify and classify cancerous lesions. Computer vision methods that use both imaging techniques could improve endoscopic diagnosis. We address the challenge of tissue classification when annotations are available only in one domain, in our case WLI, and the endoscopic images correspond to an unpaired dataset, i.e. there is no exact equivalent for every image in both NBI and WLI domains. Method: We propose a semi-surprised Generative Adversarial Network (GAN)-based method composed of three main components: a teacher network trained on the labeled WLI data; a cycle-consistency GAN to perform unpaired image-to-image translation, and a multi-input student network. To ensure the quality of the synthetic images generated by the proposed GAN we perform a detailed quantitative, and qualitative analysis with the help of specialists. Conclusion: The overall average classification accuracy, precision, and recall obtained with the proposed method for tissue classification are 0.90, 0.88, and 0.89 respectively, while the same metrics obtained in the unlabeled domain (NBI) are 0.92, 0.64, and 0.94 respectively. The quality of the generated images is reliable enough to deceive specialists. Significance: This study shows the potential of using semi-supervised GAN-based classification to improve bladder tissue classification when annotations are limited in multi-domain data.

This work presents a thorough review concerning recent studies and text generation advancements using Generative Adversarial Networks. The usage of adversarial learning for text generation is promising as it provides alternatives to generate the so-called "natural" language. Nevertheless, adversarial text generation is not a simple task as its foremost architecture, the Generative Adversarial Networks, were designed to cope with continuous information (image) instead of discrete data (text). Thus, most works are based on three possible options, i.e., Gumbel-Softmax differentiation, Reinforcement Learning, and modified training objectives. All alternatives are reviewed in this survey as they present the most recent approaches for generating text using adversarial-based techniques. The selected works were taken from renowned databases, such as Science Direct, IEEEXplore, Springer, Association for Computing Machinery, and arXiv, whereas each selected work has been critically analyzed and assessed to present its objective, methodology, and experimental results.

Machine Learning algorithms have been extensively researched throughout the last decade, leading to unprecedented advances in a broad range of applications, such as image classification and reconstruction, object recognition, and text categorization. Nonetheless, most Machine Learning algorithms are trained via derivative-based optimizers, such as the Stochastic Gradient Descent, leading to possible local optimum entrapments and inhibiting them from achieving proper performances. A bio-inspired alternative to traditional optimization techniques, denoted as meta-heuristic, has received significant attention due to its simplicity and ability to avoid local optimums imprisonment. In this work, we propose to use meta-heuristic techniques to fine-tune pre-trained weights, exploring additional regions of the search space, and improving their effectiveness. The experimental evaluation comprises two classification tasks (image and text) and is assessed under four literature datasets. Experimental results show nature-inspired algorithms' capacity in exploring the neighborhood of pre-trained weights, achieving superior results than their counterpart pre-trained architectures. Additionally, a thorough analysis of distinct architectures, such as Multi-Layer Perceptron and Recurrent Neural Networks, attempts to visualize and provide more precise insights into the most critical weights to be fine-tuned in the learning process.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Bi-encoders and cross-encoders are widely used in many state-of-the-art retrieval pipelines. In this work we study the generalization ability of these two types of architectures on a wide range of parameter count on both in-domain and out-of-domain scenarios. We find that the number of parameters and early query-document interactions of cross-encoders play a significant role in the generalization ability of retrieval models. Our experiments show that increasing model size results in marginal gains on in-domain test sets, but much larger gains in new domains never seen during fine-tuning. Furthermore, we show that cross-encoders largely outperform bi-encoders of similar size in several tasks. In the BEIR benchmark, our largest cross-encoder surpasses a state-of-the-art bi-encoder by more than 4 average points. Finally, we show that using bi-encoders as first-stage retrievers provides no gains in comparison to a simpler retriever such as BM25 on out-of-domain tasks. The code is available at https://github.com/guilhermemr04/scaling-zero-shot-retrieval.git

Crypto-coins (also known as cryptocurrencies) are tradable digital assets. Notable examples include Bitcoin, Ether and Litecoin. Ownerships of cryptocoins are registered on distributed ledgers (i.e., blockchains). Secure encryption techniques guarantee the security of the transactions (transfers of coins across owners), registered into the ledger. Cryptocoins are exchanged for specific trading prices. While history has shown the extreme volatility of such trading prices across all different sets of crypto-assets, it remains unclear what and if there are tight relations between the trading prices of different cryptocoins. Major coin exchanges (i.e., Coinbase) provide trend correlation indicators to coin owners, suggesting possible acquisitions or sells. However, these correlations remain largely unvalidated. In this paper, we shed lights on the trend correlations across a large variety of cryptocoins, by investigating their coin-price correlation trends over a period of two years. Our experimental results suggest strong correlation patterns between main coins (Ethereum, Bitcoin) and alt-coins. We believe our study can support forecasting techniques for time-series modeling in the context of crypto-coins. We release our dataset and code to reproduce our analysis to the research community.

In the last decade, exponential data growth supplied machine learning-based algorithms' capacity and enabled their usage in daily-life activities. Additionally, such an improvement is partially explained due to the advent of deep learning techniques, i.e., stacks of simple architectures that end up in more complex models. Although both factors produce outstanding results, they also pose drawbacks regarding the learning process as training complex models over large datasets are expensive and time-consuming. Such a problem is even more evident when dealing with video analysis. Some works have considered transfer learning or domain adaptation, i.e., approaches that map the knowledge from one domain to another, to ease the training burden, yet most of them operate over individual or small blocks of frames. This paper proposes a novel approach to map the knowledge from action recognition to event recognition using an energy-based model, denoted as Spectral Deep Belief Network. Such a model can process all frames simultaneously, carrying spatial and temporal information through the learning process. The experimental results conducted over two public video dataset, the HMDB-51 and the UCF-101, depict the effectiveness of the proposed model and its reduced computational burden when compared to traditional energy-based models, such as Restricted Boltzmann Machines and Deep Belief Networks.

This letter focuses on the task of Multi-Target Multi-Camera vehicle tracking. We propose to associate single-camera trajectories into multi-camera global trajectories by training a Graph Convolutional Network. Our approach simultaneously processes all cameras providing a global solution, and it is also robust to large cameras unsynchronizations. Furthermore, we design a new loss function to deal with class imbalance. Our proposal outperforms the related work showing better generalization and without requiring ad-hoc manual annotations or thresholds, unlike compared approaches.