尽管在利用深度学习来自动化胸部X光片解释和疾病诊断任务方面取得了进展，但顺序胸部X射线（CXR）之间的变化受到了有限的关注。监测通过胸部成像可视化的病理的进展在解剖运动估计和图像注册中构成了几个挑战，即在空间上对齐这两个图像并在变化检测中对时间动力学进行建模。在这项工作中，我们提出了Chexrelnet，这是一种可以跟踪两个CXR之间纵向病理关系的神经模型。Chexrelnet结合了局部和全球视觉特征，利用图像间和图像内的解剖信息，并学习解剖区域属性之间的依赖性，以准确预测一对CXR的疾病变化。与基准相比，胸部成像组数据集的实验结果显示下游性能提高。代码可从https://github.com/plan-lab/chexrelnet获得

卷积层和损耗功能是深度学习中的两个基本组件。由于传统的深度学习内核的成功，尽管它们可以提供不同频率，方向和比例的不同频率，方向和尺度的丰富功能，但较不可能的Gabor内核变得不那么受欢迎。对于多级图像分割的现有损失函数，通常有准确性，鲁棒性对超参数的折衷以及用于组合不同损失的手动选择。因此，为了获得使用Gabor核心的益处，同时保持深度学习中的自动特征生成的优势，我们提出了一种完全可训练的Gabor的卷积层，其中所有Gabor参数都是通过BackPropagation培训的。此外，我们基于Pearson的相关系数提出了一种损失函数，这是准确的，对学习速率的准确，鲁棒性，并且不需要手动重量选择。在43d脑磁共振图像上的实验，具有19个解剖结构，表明，使用所提出的损失功能与常规和基于Gabor的内核的适当组合，我们可以训练只有160万参数的网络，以实现83的平均骰子系数％。该尺寸比V-NET小44倍，具有7100万参数。本文展示了在深度学习3D分割中使用学习参数核的潜力。

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse images to build representations of both small-scale features (e.g., the presence of cells or blood vessels) and global properties of an image (e.g., which brain region the image comes from) is a crucial and open challenge. However, most existing datasets and benchmarks for neuroanatomy consider only a single downstream task at a time. To bridge this gap, we introduce a new dataset, annotations, and multiple downstream tasks that provide diverse ways to readout information about brain structure and architecture from the same image. Our multi-task neuroimaging benchmark (MTNeuro) is built on volumetric, micrometer-resolution X-ray microtomography images spanning a large thalamocortical section of mouse brain, encompassing multiple cortical and subcortical regions. We generated a number of different prediction challenges and evaluated several supervised and self-supervised models for brain-region prediction and pixel-level semantic segmentation of microstructures. Our experiments not only highlight the rich heterogeneity of this dataset, but also provide insights into how self-supervised approaches can be used to learn representations that capture multiple attributes of a single image and perform well on a variety of downstream tasks. Datasets, code, and pre-trained baseline models are provided at: https://mtneuro.github.io/ .

Osteoarthritis (OA) is the most prevalent chronic joint disease worldwide, where knee OA takes more than 80% of commonly affected joints. Knee OA is not a curable disease yet, and it affects large columns of patients, making it costly to patients and healthcare systems. Etiology, diagnosis, and treatment of knee OA might be argued by variability in its clinical and physical manifestations. Although knee OA carries a list of well-known terminology aiming to standardize the nomenclature of the diagnosis, prognosis, treatment, and clinical outcomes of the chronic joint disease, in practice there is a wide range of terminology associated with knee OA across different data sources, including but not limited to biomedical literature, clinical notes, healthcare literacy, and health-related social media. Among these data sources, the scientific articles published in the biomedical literature usually make a principled pipeline to study disease. Rapid yet, accurate text mining on large-scale scientific literature may discover novel knowledge and terminology to better understand knee OA and to improve the quality of knee OA diagnosis, prevention, and treatment. The present works aim to utilize artificial neural network strategies to automatically extract vocabularies associated with knee OA diseases. Our finding indicates the feasibility of developing word embedding neural networks for autonomous keyword extraction and abstraction of knee OA.

Designing a local planner to control tractor-trailer vehicles in forward and backward maneuvering is a challenging control problem in the research community of autonomous driving systems. Considering a critical situation in the stability of tractor-trailer systems, a practical and novel approach is presented to design a non-linear MPC(NMPC) local planner for tractor-trailer autonomous vehicles in both forward and backward maneuvering. The tractor velocity and steering angle are considered to be control variables. The proposed NMPC local planner is designed to handle jackknife situations, avoiding multiple static obstacles, and path following in both forward and backward maneuvering. The challenges mentioned above are converted into a constrained problem that can be handled simultaneously by the proposed NMPC local planner. The direct multiple shooting approach is used to convert the optimal control problem(OCP) into a non-linear programming problem(NLP) that IPOPT solvers can solve in CasADi. The controller performance is evaluated through different backup and forward maneuvering scenarios in the Gazebo simulation environment in real-time. It achieves asymptotic stability in avoiding static obstacles and accurate tracking performance while respecting path constraints. Finally, the proposed NMPC local planner is integrated with an open-source autonomous driving software stack called AutowareAi.

Fine-tuning a Pre-trained Language Model (PLM) on a specific downstream task has been a well-known paradigm in Natural Language Processing. However, with the ever-growing size of PLMs, training the entire model on several downstream tasks becomes very expensive and resource-hungry. Recently, different Parameter Efficient Tuning (PET) techniques are proposed to improve the efficiency of fine-tuning PLMs. One popular category of PET methods is the low-rank adaptation methods which insert learnable truncated SVD modules into the original model either sequentially or in parallel. However, low-rank decomposition suffers from limited representation power. In this work, we address this problem using the Kronecker product instead of the low-rank representation. We introduce KronA, a Kronecker product-based adapter module for efficient fine-tuning of Transformer-based PLMs. We apply the proposed methods for fine-tuning T5 on the GLUE benchmark to show that incorporating the Kronecker-based modules can outperform state-of-the-art PET methods.

Prior work has shown that coupling sequential latent variable models with semantic ontological knowledge can improve the representational capabilities of event modeling approaches. In this work, we present a novel, doubly hierarchical, semi-supervised event modeling framework that provides structural hierarchy while also accounting for ontological hierarchy. Our approach consists of multiple layers of structured latent variables, where each successive layer compresses and abstracts the previous layers. We guide this compression through the injection of structured ontological knowledge that is defined at the type level of events: importantly, our model allows for partial injection of semantic knowledge and it does not depend on observing instances at any particular level of the semantic ontology. Across two different datasets and four different evaluation metrics, we demonstrate that our approach is able to out-perform the previous state-of-the-art approaches, demonstrating the benefits of structured and semantic hierarchical knowledge for event modeling.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Scaling up neural networks has led to remarkable performance across a wide range of tasks. Moreover, performance often follows reliable scaling laws as a function of training set size, model size, and compute, which offers valuable guidance as large-scale experiments are becoming increasingly expensive. However, previous work on scaling laws has primarily used private data \& models or focused on uni-modal language or vision learning. To address these limitations, we investigate scaling laws for contrastive language-image pre-training (CLIP) with the public LAION dataset and the open-source OpenCLIP repository. Our large-scale experiments involve models trained on up to two billion image-text pairs and identify power law scaling for multiple downstream tasks including zero-shot classification, retrieval, linear probing, and end-to-end fine-tuning. We find that the training distribution plays a key role in scaling laws as the OpenAI and OpenCLIP models exhibit different scaling behavior despite identical model architectures and similar training recipes. We open-source our evaluation workflow and all models, including the largest public CLIP models, to ensure reproducibility and make scaling laws research more accessible. Source code and instructions to reproduce this study will be available at https://github.com/LAION-AI/scaling-laws-openclip

Metaverse over wireless networks is an emerging use case of the sixth generation (6G) wireless systems, posing unprecedented challenges in terms of its multi-modal data transmissions with stringent latency and reliability requirements. Towards enabling this wireless metaverse, in this article we propose a novel semantic communication (SC) framework by decomposing the metaverse into human/machine agent-specific semantic multiverses (SMs). An SM stored at each agent comprises a semantic encoder and a generator, leveraging recent advances in generative artificial intelligence (AI). To improve communication efficiency, the encoder learns the semantic representations (SRs) of multi-modal data, while the generator learns how to manipulate them for locally rendering scenes and interactions in the metaverse. Since these learned SMs are biased towards local environments, their success hinges on synchronizing heterogeneous SMs in the background while communicating SRs in the foreground, turning the wireless metaverse problem into the problem of semantic multiverse communication (SMC). Based on this SMC architecture, we propose several promising algorithmic and analytic tools for modeling and designing SMC, ranging from distributed learning and multi-agent reinforcement learning (MARL) to signaling games and symbolic AI.