We develop a Bayesian semi-parametric model for the estimating the impact of dynamic treatment rules on survival among patients diagnosed with pediatric acute myeloid leukemia (AML). The data consist of a subset of patients enrolled in the phase III AAML1031 clinical trial in which patients move through a sequence of four treatment courses. At each course, they undergo treatment that may or may not include anthracyclines (ACT). While ACT is known to be effective at treating AML, it is also cardiotoxic and can lead to early death for some patients. Our task is to estimate the potential survival probability under hypothetical dynamic ACT treatment strategies, but there are several impediments. First, since ACT was not randomized in the trial, its effect on survival is confounded over time. Second, subjects initiate the next course depending on when they recover from the previous course, making timing potentially informative of subsequent treatment and survival. Third, patients may die or drop out before ever completing the full treatment sequence. We develop a generative Bayesian semi-parametric model based on Gamma Process priors to address these complexities. At each treatment course, the model captures subjects' transition to subsequent treatment or death in continuous time under a given rule. A g-computation procedure is used to compute a posterior over potential survival probability that is adjusted for time-varying confounding. Using this approach, we conduct posterior inference for the efficacy of hypothetical treatment rules that dynamically modify ACT based on evolving cardiac function.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

我们介绍了BenchClamp，这是一种评估受约束语言模型解析的基准测试，该基准通过通过限制性解码的启动或微调语言模型来基于输入文本的分析来产生语义输出。目前，预审前语言模型的开发人员基于分类，跨度提取和自由文本生成任务。语言解析在语言模型评估中被忽略，因为处理特定于任务的体系结构和表示的复杂性。最近的工作表明，当输出被限制为有效的语义表示时，从提示或微调的语言模型中产生的发电能力可以很好地表现。台式设备包括无上下文的语法，适用于六个具有不同输出含义表示形式的语义解析数据集，以及一个受约束的解码接口，以生成这些语法覆盖的输出。我们为每个数据集提供低，中和高资源分割，从而可以在不同的数据制度下准确比较各种语言模型。我们的基准测试既支持基于及时的学习又支持微调，并为语言模型开发人员提供了易于使用的工具包，以评估语义解析。

The usage of technologically advanced devices has seen a boom in many domains, including education, automation, and healthcare; with most of the services requiring Internet connectivity. To secure a network, device identification plays key role. In this paper, a device fingerprinting (DFP) model, which is able to distinguish between Internet of Things (IoT) and non-IoT devices, as well as uniquely identify individual devices, has been proposed. Four statistical features have been extracted from the consecutive five device-originated packets, to generate individual device fingerprints. The method has been evaluated using the Random Forest (RF) classifier and different datasets. Experimental results have shown that the proposed method achieves up to 99.8% accuracy in distinguishing between IoT and non-IoT devices and over 97.6% in classifying individual devices. These signify that the proposed method is useful in assisting operators in making their networks more secure and robust to security breaches and unauthorized access.

We explore the use of large language models (LLMs) for zero-shot semantic parsing. Semantic parsing involves mapping natural language utterances to task-specific meaning representations. Language models are generally trained on the publicly available text and code and cannot be expected to directly generalize to domain-specific parsing tasks in a zero-shot setting. In this work, we propose ZEROTOP, a zero-shot task-oriented parsing method that decomposes a semantic parsing problem into a set of abstractive and extractive question-answering (QA) problems, enabling us to leverage the ability of LLMs to zero-shot answer reading comprehension questions. For each utterance, we prompt the LLM with questions corresponding to its top-level intent and a set of slots and use the LLM generations to construct the target meaning representation. We observe that current LLMs fail to detect unanswerable questions; and as a result, cannot handle questions corresponding to missing slots. To address this problem, we fine-tune a language model on public QA datasets using synthetic negative samples. Experimental results show that our QA-based decomposition paired with the fine-tuned LLM can correctly parse ~16% of utterances in the MTOP dataset without requiring any annotated data.

Language modeling, a central task in natural language processing, involves estimating a probability distribution over strings. In most cases, the estimated distribution sums to 1 over all finite strings. However, in some pathological cases, probability mass can ``leak'' onto the set of infinite sequences. In order to characterize the notion of leakage more precisely, this paper offers a measure-theoretic treatment of language modeling. We prove that many popular language model families are in fact tight, meaning that they will not leak in this sense. We also generalize characterizations of tightness proposed in previous works.

From smoothly pursuing moving objects to rapidly shifting gazes during visual search, humans employ a wide variety of eye movement strategies in different contexts. While eye movements provide a rich window into mental processes, building generative models of eye movements is notoriously difficult, and to date the computational objectives guiding eye movements remain largely a mystery. In this work, we tackled these problems in the context of a canonical spatial planning task, maze-solving. We collected eye movement data from human subjects and built deep generative models of eye movements using a novel differentiable architecture for gaze fixations and gaze shifts. We found that human eye movements are best predicted by a model that is optimized not to perform the task as efficiently as possible but instead to run an internal simulation of an object traversing the maze. This not only provides a generative model of eye movements in this task but also suggests a computational theory for how humans solve the task, namely that humans use mental simulation.

The findable, accessible, interoperable, and reusable (FAIR) data principles have provided a framework for examining, evaluating, and improving how we share data with the aim of facilitating scientific discovery. Efforts have been made to generalize these principles to research software and other digital products. Artificial intelligence (AI) models -- algorithms that have been trained on data rather than explicitly programmed -- are an important target for this because of the ever-increasing pace with which AI is transforming scientific and engineering domains. In this paper, we propose a practical definition of FAIR principles for AI models and create a FAIR AI project template that promotes adherence to these principles. We demonstrate how to implement these principles using a concrete example from experimental high energy physics: a graph neural network for identifying Higgs bosons decaying to bottom quarks. We study the robustness of these FAIR AI models and their portability across hardware architectures and software frameworks, and report new insights on the interpretability of AI predictions by studying the interplay between FAIR datasets and AI models. Enabled by publishing FAIR AI models, these studies pave the way toward reliable and automated AI-driven scientific discovery.

Athletes routinely undergo fitness evaluations to evaluate their training progress. Typically, these evaluations require a trained professional who utilizes specialized equipment like force plates. For the assessment, athletes perform drop and squat jumps, and key variables are measured, e.g. velocity, flight time, and time to stabilization, to name a few. However, amateur athletes may not have access to professionals or equipment that can provide these assessments. Here, we investigate the feasibility of estimating key variables using video recordings. We focus on jump velocity as a starting point because it is highly correlated with other key variables and is important for determining posture and lower-limb capacity. We find that velocity can be estimated with a high degree of precision across a range of athletes, with an average R-value of 0.71 (SD = 0.06).

Source-free domain adaptation (SFDA) aims to transfer knowledge learned from a source domain to an unlabeled target domain, where the source data is unavailable during adaptation. Existing approaches for SFDA focus on self-training usually including well-established entropy minimization techniques. One of the main challenges in SFDA is to reduce accumulation of errors caused by domain misalignment. A recent strategy successfully managed to reduce error accumulation by pseudo-labeling the target samples based on class-wise prototypes (centroids) generated by their clustering in the representation space. However, this strategy also creates cases for which the cross-entropy of a pseudo-label and the minimum entropy have a conflict in their objectives. We call this conflict the centroid-hypothesis conflict. We propose to reconcile this conflict by aligning the entropy minimization objective with that of the pseudo labels' cross entropy. We demonstrate the effectiveness of aligning the two loss objectives on three domain adaptation datasets. In addition, we provide state-of-the-art results using up-to-date architectures also showing the consistency of our method across these architectures.