Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays, researchers have moved their interest towards AD detection from spontaneous speech, since it constitutes a time-effective procedure. However, existing state-of-the-art works proposing multimodal approaches do not take into consideration the inter- and intra-modal interactions and propose early and late fusion approaches. To tackle these limitations, we propose deep neural networks, which can be trained in an end-to-end trainable way and capture the inter- and intra-modal interactions. Firstly, each audio file is converted to an image consisting of three channels, i.e., log-Mel spectrogram, delta, and delta-delta. Next, each transcript is passed through a BERT model followed by a gated self-attention layer. Similarly, each image is passed through a Swin Transformer followed by an independent gated self-attention layer. Acoustic features are extracted also from each audio file. Finally, the representation vectors from the different modalities are fed to a tensor fusion layer for capturing the inter-modal interactions. Extensive experiments conducted on the ADReSS Challenge dataset indicate that our introduced approaches obtain valuable advantages over existing research initiatives reaching Accuracy and F1-score up to 86.25% and 85.48% respectively.

阿尔茨海默氏病（AD）构成了一种神经退行性疾病，对人们的日常生活造成了严重后果，如果没有可用的治愈方法，请及早诊断出来。阿尔茨海默氏症是痴呆症的最常见原因，它构成了记忆丧失的一般术语。由于痴呆症会影响言语，因此现有的研究计划着重于检测自发言语的痴呆症。然而，关于语音数据转换为对数 - 梅尔频谱图和梅尔频率cepstral系数（MFCC）以及预验证模型的使用，几乎没有做出的工作。同时，关于变压器网络的使用以及两种模式（即语音和笔录）的方式，几乎没有完成工作。为了解决这些局限性，首先我们采用了几个验证的模型，而视觉变压器（VIT）则取得了最高的评估结果。其次，我们提出了多模型模型。更具体地说，我们引入的模型包括封闭式的多模式单元，以控制每种模态对最终分类和跨模式关注的影响，以便以有效的方式捕获两种模态之间的关系。在Adress挑战数据集上进行的广泛实验证明了所提出的模型的有效性及其优于最先进的方法。

阿尔茨海默氏病（AD）是痴呆症的主要原因，伴随着记忆力的丧失，如果未按时诊断，可能会导致人们的日常生活造成严重后果。很少有作品利用基于变压器的网络，尽管获得了高度的精度，但在模型可解释性方面几乎没有完成工作。此外，尽管迷你精神状态考试（MMSE）分数与痴呆症的识别密不可分，但研究工作面临着痴呆症鉴定的任务以及将MMSE分数作为两个独立任务的预测任务。为了解决这些局限性，我们采用了几种基于变压器的模型，伯特（Bert）的准确性最高为87.50％。同时，我们提出了一种可解释的方法来检测基于暹罗网络的准确性高达83.75％的患者。接下来，我们介绍了两个多任务学习模型，其中主要任务是指痴呆症的识别（二进制分类），而辅助辅助学则对应于痴呆症的严重程度（多类分类）。我们的模型在多任务学习环境中检测AD患者的准确度等于86.25％。最后，我们提出了一些新方法，以识别AD患者和非AD的语言模式，包括文本统计，词汇唯一性，单词用法，通过详细的语言分析和解释性技术（LIME）（LIME）。发现表明AD和非AD患者之间的语言差异显着差异。

Real-world robotic grasping can be done robustly if a complete 3D Point Cloud Data (PCD) of an object is available. However, in practice, PCDs are often incomplete when objects are viewed from few and sparse viewpoints before the grasping action, leading to the generation of wrong or inaccurate grasp poses. We propose a novel grasping strategy, named 3DSGrasp, that predicts the missing geometry from the partial PCD to produce reliable grasp poses. Our proposed PCD completion network is a Transformer-based encoder-decoder network with an Offset-Attention layer. Our network is inherently invariant to the object pose and point's permutation, which generates PCDs that are geometrically consistent and completed properly. Experiments on a wide range of partial PCD show that 3DSGrasp outperforms the best state-of-the-art method on PCD completion tasks and largely improves the grasping success rate in real-world scenarios. The code and dataset will be made available upon acceptance.

Transformers are becoming increasingly popular due to their superior performance over conventional convolutional neural networks(CNNs). However, transformers usually require a much larger amount of memory to train than CNNs, which prevents their application in many low resource settings. Local learning, which divides the network into several distinct modules and trains them individually, is a promising alternative to the end-to-end (E2E) training approach to reduce the amount of memory for training and to increase parallelism. This paper is the first to apply Local Learning on transformers for this purpose. The standard CNN-based local learning method, InfoPro [32], reconstructs the input images for each module in a CNN. However, reconstructing the entire image does not generalize well. In this paper, we propose a new mechanism for each local module, where instead of reconstructing the entire image, we reconstruct its input features, generated from previous modules. We evaluate our approach on 4 commonly used datasets and 3 commonly used decoder structures on Swin-Tiny. The experiments show that our approach outperforms InfoPro-Transformer, the InfoPro with Transfomer backbone we introduced, by at up to 0.58% on CIFAR-10, CIFAR-100, STL-10 and SVHN datasets, while using up to 12% less memory. Compared to the E2E approach, we require 36% less GPU memory when the network is divided into 2 modules and 45% less GPU memory when the network is divided into 4 modules.

Dense prediction tasks such as segmentation and detection of pathological entities hold crucial clinical value in the digital pathology workflow. However, obtaining dense annotations on large cohorts is usually tedious and expensive. Contrastive learning (CL) is thus often employed to leverage large volumes of unlabeled data to pre-train the backbone network. To boost CL for dense prediction, some studies have proposed variations of dense matching objectives in pre-training. However, our analysis shows that employing existing dense matching strategies on histopathology images enforces invariance among incorrect pairs of dense features and, thus, is imprecise. To address this, we propose a precise location-based matching mechanism that utilizes the overlapping information between geometric transformations to precisely match regions in two augmentations. Extensive experiments on two pretraining datasets (TCGA-BRCA, NCT-CRC-HE) and three downstream datasets (GlaS, CRAG, BCSS) highlight the superiority of our method in semantic and instance segmentation tasks. Our method outperforms previous dense matching methods by up to 7.2 % in average precision for detection and 5.6 % in average precision for instance segmentation tasks. Additionally, by using our matching mechanism in the three popular contrastive learning frameworks, MoCo-v2, VICRegL and ConCL, the average precision in detection is improved by 0.7 % to 5.2 % and the average precision in segmentation is improved by 0.7 % to 4.0 %, demonstrating its generalizability.

This paper extends quantile factor analysis to a probabilistic variant that incorporates regularization and computationally efficient variational approximations. By means of synthetic and real data experiments it is established that the proposed estimator can achieve, in many cases, better accuracy than a recently proposed loss-based estimator. We contribute to the literature on measuring uncertainty by extracting new indexes of low, medium and high economic policy uncertainty, using the probabilistic quantile factor methodology. Medium and high indexes have clear contractionary effects, while the low index is benign for the economy, showing that not all manifestations of uncertainty are the same.

Automatic fake news detection is a challenging problem in misinformation spreading, and it has tremendous real-world political and social impacts. Past studies have proposed machine learning-based methods for detecting such fake news, focusing on different properties of the published news articles, such as linguistic characteristics of the actual content, which however have limitations due to the apparent language barriers. Departing from such efforts, we propose FNDaaS, the first automatic, content-agnostic fake news detection method, that considers new and unstudied features such as network and structural characteristics per news website. This method can be enforced as-a-Service, either at the ISP-side for easier scalability and maintenance, or user-side for better end-user privacy. We demonstrate the efficacy of our method using data crawled from existing lists of 637 fake and 1183 real news websites, and by building and testing a proof of concept system that materializes our proposal. Our analysis of data collected from these websites shows that the vast majority of fake news domains are very young and appear to have lower time periods of an IP associated with their domain than real news ones. By conducting various experiments with machine learning classifiers, we demonstrate that FNDaaS can achieve an AUC score of up to 0.967 on past sites, and up to 77-92% accuracy on newly-flagged ones.

Recent works on diffusion models have demonstrated a strong capability for conditioning image generation, e.g., text-guided image synthesis. Such success inspires many efforts trying to use large-scale pre-trained diffusion models for tackling a challenging problem--real image editing. Works conducted in this area learn a unique textual token corresponding to several images containing the same object. However, under many circumstances, only one image is available, such as the painting of the Girl with a Pearl Earring. Using existing works on fine-tuning the pre-trained diffusion models with a single image causes severe overfitting issues. The information leakage from the pre-trained diffusion models makes editing can not keep the same content as the given image while creating new features depicted by the language guidance. This work aims to address the problem of single-image editing. We propose a novel model-based guidance built upon the classifier-free guidance so that the knowledge from the model trained on a single image can be distilled into the pre-trained diffusion model, enabling content creation even with one given image. Additionally, we propose a patch-based fine-tuning that can effectively help the model generate images of arbitrary resolution. We provide extensive experiments to validate the design choices of our approach and show promising editing capabilities, including changing style, content addition, and object manipulation. The code is available for research purposes at https://github.com/zhang-zx/SINE.git .

Can a text-to-image diffusion model be used as a training objective for adapting a GAN generator to another domain? In this paper, we show that the classifier-free guidance can be leveraged as a critic and enable generators to distill knowledge from large-scale text-to-image diffusion models. Generators can be efficiently shifted into new domains indicated by text prompts without access to groundtruth samples from target domains. We demonstrate the effectiveness and controllability of our method through extensive experiments. Although not trained to minimize CLIP loss, our model achieves equally high CLIP scores and significantly lower FID than prior work on short prompts, and outperforms the baseline qualitatively and quantitatively on long and complicated prompts. To our best knowledge, the proposed method is the first attempt at incorporating large-scale pre-trained diffusion models and distillation sampling for text-driven image generator domain adaptation and gives a quality previously beyond possible. Moreover, we extend our work to 3D-aware style-based generators and DreamBooth guidance.