System logs are a common source of monitoring data for analyzing computing systems' behavior. Due to the complexity of modern computing systems and the large size of collected monitoring data, automated analysis mechanisms are required. Numerous machine learning and deep learning methods are proposed to address this challenge. However, due to the existence of sensitive data in system logs their analysis and storage raise serious privacy concerns. Anonymization methods could be used to clean the monitoring data before analysis. However, anonymized system logs, in general, do not provide adequate usefulness for the majority of behavioral analysis. Content-aware anonymization mechanisms such as PaRS preserve the correlation of system logs even after anonymization. This work evaluates the usefulness of anonymized system logs taken from the Taurus HPC cluster anonymized using PaRS, for behavioral analysis via recurrent neural network models.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

目的：本研究评估了市售可解释的AI算法在增强临床医生在胸部X射线（CXR）上鉴定肺癌的能力的影响。设计：这项回顾性研究评估了11位临床医生在胸部X光片中检测肺癌的表现，并在有和没有市售的AI算法的帮助下（红点，观察到），预测CXRS可疑的肺癌。根据临床确定的诊断评估了临床医生的表现。设置：该研究分析了NHS医院的匿名患者数据；该数据集由成年患者（18岁及以上）的400张胸部X光片组成，他们在2020年进行了CXR，并提供相应的临床文本报告。参与者：由11位临床医生（放射科医生，放射科医生受训者和报告射线照相师）组成的读者小组参加。主要结果指标：临床医生在CXR上检测肺癌的总体准确性，敏感性，特异性和精度，有或没有AI输入。还评估了有或没有AI输入的临床医生与绩效标准偏差之间的协议率。结果：临床医生对AI算法的使用导致肺部肿瘤检测的总体性能提高，从而达到了在CXR上鉴定出的肺癌的总体增长17.4％ ，分别增加了13％和13％的阶段1和2期肺癌的检测，以及临床医生表现的标准化。结论：这项研究在AI算法的临床实用性方面表现出了巨大的希望，可以通过整体改善读者表现来改善早期肺癌诊断和促进健康平等，而不会影响下游成像资源。

主动学习（AL）算法旨在识别注释的最佳数据子集，使得深神经网络（DNN）在此标记子集上培训时可以实现更好的性能。 AL特别有影响的工业规模设置，其中数据标签成本高，从业者使用各种工具来处理，以提高模型性能。最近自我监督预测（SSP）的成功突出了利用丰富的未标记数据促进模型性能的重要性。通过将AL与SSP结合起来，我们可以使用未标记的数据，同时标记和培训特别是信息样本。在这项工作中，我们研究了Imagenet上的AL和SSP的组合。我们发现小型玩具数据集上的性能 - 文献中的典型基准设置 - 由于活动学习者选择的类不平衡样本，而不是想象中的性能。在我们测试的现有基线中，各种小型和大规​​模设置的流行AL算法未能以随机抽样优于差异。为了解决类别不平衡问题，我们提出了平衡选择（基础），这是一种简单，可伸缩的AL算法，通过选择比现有方法更加平衡样本来始终如一地始终采样。我们的代码可用于：https://github.com/zeyademam/active_learning。

深度加强学习（RL）的最新进展导致许多2人零和游戏中的相当大的进展，如去，扑克和星际争霸。这种游戏的纯粹对抗性质允许概念上简单地应用R1方法。然而，现实世界的设置是许多代理商，代理交互是复杂的共同利益和竞争方面的混合物。我们认为外交，一个旨在突出由多种代理交互导致的困境的7人棋盘游戏。它还具有大型组合动作空间和同时移动，这对RL算法具有具有挑战性。我们提出了一个简单但有效的近似最佳响应操作员，旨在处理大型组合动作空间并同时移动。我们还介绍了一系列近似虚构游戏的政策迭代方法。通过这些方法，我们成功地将RL申请到外交：我们认为我们的代理商令人信服地令人信服地表明，游戏理论均衡分析表明新过程产生了一致的改进。

A Digital Twin (DT) is a simulation of a physical system that provides information to make decisions that add economic, social or commercial value. The behaviour of a physical system changes over time, a DT must therefore be continually updated with data from the physical systems to reflect its changing behaviour. For resource-constrained systems, updating a DT is non-trivial because of challenges such as on-board learning and the off-board data transfer. This paper presents a framework for updating data-driven DTs of resource-constrained systems geared towards system health monitoring. The proposed solution consists of: (1) an on-board system running a light-weight DT allowing the prioritisation and parsimonious transfer of data generated by the physical system; and (2) off-board robust updating of the DT and detection of anomalous behaviours. Two case studies are considered using a production gas turbine engine system to demonstrate the digital representation accuracy for real-world, time-varying physical systems.

Learning to predict masked tokens in a sequence has been shown to be a powerful pretraining objective for large-scale language models. After training, such masked language models can provide distributions of tokens conditioned on bidirectional context. In this short draft, we show that such bidirectional conditionals often demonstrate considerable inconsistencies, i.e., they can not be derived from a coherent joint distribution when considered together. We empirically quantify such inconsistencies in the simple scenario of bigrams for two common styles of masked language models: T5-style and BERT-style. For example, we show that T5 models often confuse its own preference regarding two similar bigrams. Such inconsistencies may represent a theoretical pitfall for the research work on sampling sequences based on the bidirectional conditionals learned by BERT-style MLMs. This phenomenon also means that T5-style MLMs capable of infilling will generate discrepant results depending on how much masking is given, which may represent a particular trust issue.

We study the problem of planning under model uncertainty in an online meta-reinforcement learning (RL) setting where an agent is presented with a sequence of related tasks with limited interactions per task. The agent can use its experience in each task and across tasks to estimate both the transition model and the distribution over tasks. We propose an algorithm to meta-learn the underlying structure across tasks, utilize it to plan in each task, and upper-bound the regret of the planning loss. Our bound suggests that the average regret over tasks decreases as the number of tasks increases and as the tasks are more similar. In the classical single-task setting, it is known that the planning horizon should depend on the estimated model's accuracy, that is, on the number of samples within task. We generalize this finding to meta-RL and study this dependence of planning horizons on the number of tasks. Based on our theoretical findings, we derive heuristics for selecting slowly increasing discount factors, and we validate its significance empirically.

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the gap between the number of imaging exams and the number of expert radiologist readers required to cover this increase will continue to expand, consequently introducing a demand for AI-based tools that improve the efficiency with which radiologists can comfortably interpret these exams. AI has been shown to improve efficiency in medical-image generation, processing, and interpretation, and a variety of such AI models have been developed across research labs worldwide. However, very few of these, if any, find their way into routine clinical use, a discrepancy that reflects the divide between AI research and successful AI translation. To address the barrier to clinical deployment, we have formed MONAI Consortium, an open-source community which is building standards for AI deployment in healthcare institutions, and developing tools and infrastructure to facilitate their implementation. This report represents several years of weekly discussions and hands-on problem solving experience by groups of industry experts and clinicians in the MONAI Consortium. We identify barriers between AI-model development in research labs and subsequent clinical deployment and propose solutions. Our report provides guidance on processes which take an imaging AI model from development to clinical implementation in a healthcare institution. We discuss various AI integration points in a clinical Radiology workflow. We also present a taxonomy of Radiology AI use-cases. Through this report, we intend to educate the stakeholders in healthcare and AI (AI researchers, radiologists, imaging informaticists, and regulators) about cross-disciplinary challenges and possible solutions.