病毒感染导致全世界的显着发病率和死亡率。理解特定病毒和人类蛋白质之间的相互作用模式在揭示病毒感染和发病机制的潜在机制方面发挥着至关重要的作用。这可以进一步帮助预防和治疗病毒相关疾病。然而，由于病毒 - 人类相互作用的稀缺数据和大多数病毒的快速突变率，预测新病毒和人体细胞之间的蛋白质 - 蛋白质相互作用的任务是非常挑战性的。我们开发了一种多任务转移学习方法，利用人类互乱组约2400万蛋白序列和相互作用模式的信息来解决小型训练数据集的问题。除了使用手工制作的蛋白质特征，而不是通过深语模型方法从巨大的蛋白质序列来源学习的统计学上丰富的蛋白质表示。此外，我们采用了额外的目的，旨在最大限度地提高观察人蛋白质蛋白质相互作用的可能性。这一附加任务目标充当规律器，还允许纳入域知识来告知病毒 - 人蛋白质 - 蛋白质相互作用预测模型。我们的方法在13个基准数据集中实现了竞争力，以及SAR-COV-2病毒受体的案例研究。实验结果表明，我们所提出的模型有效地用于病毒 - 人和细菌 - 人蛋白质 - 蛋白质 - 蛋白质相互作用预测任务。我们分享我们的重复性和未来研究代码，以便在https://git.l3s.uni-hannover.de/dong/multitastastastastastastastastastask-transfer。

来自最近的研究的日益增长的证据意味着MicroRNA或miRNA可以作为各种复杂人类疾病中的生物标志物。由于湿实验室实验昂贵且耗时，MiRNA疾病协会预测的计算技术近年来引起了很多关注。数据稀缺是建立可靠机器学习模式的主要挑战之一。数据稀缺结合使用预先计算的手工制作输入功能导致了过度装备和数据泄漏的问题。我们通过提出一种基于新的多任务图卷积的方法来克服现有作品的局限性，我们称之为粘基。杀菌允许自动特征提取，同时将知识与五个异质生物信息来源（miRNA /疾病和蛋白质编码基因（PCG）之间的相互作用，多任务设置中的蛋白质编码基因，miRNA家族信息和病理学之间的相互作用。这是一种新颖的视角，并未在之前进行过。为了有效地测试我们模型的泛化能力，我们在标准基准数据集中构建了大规模实验，以及我们提出的更大的独立测试集和案例研究。杀螨物显示出在HMDDV2.0和HMDDV3.0数据集上的5倍CV评估中的至少3％，并且在较大独立的测试集上至少35％，并在最先进的方法上具有看不见的miRNA和疾病。我们分享我们的重复性和未来研究代码，以便在https://git.l3s.uni-hannover.de/dong/cmtt。

This study proposes an approach for establishing an optimal multihop ad-hoc network using multiple unmanned aerial vehicles (UAVs) to provide emergency communication in disaster areas. The approach includes two stages, one uses particle swarm optimization (PSO) to find optimal positions to deploy UAVs, and the other uses a behavior-based controller to navigate the UAVs to their assigned positions without colliding with obstacles in an unknown environment. Several constraints related to the UAVs' sensing and communication ranges have been imposed to ensure the applicability of the proposed approach in real-world scenarios. A number of simulation experiments with data loaded from real environments have been conducted. The results show that our proposed approach is not only successful in establishing multihop ad-hoc routes but also meets the requirements for real-time deployment of UAVs.

人表皮生长因子受体2（HER2）生物标志物的免疫组织化学（IHC）染色在乳腺组织分析，临床前研究和诊断决策中广泛实践，指导癌症治疗和发病机制调查。 HER2染色需要由组织医学表演表演的艰苦组织处理和化学处理，这通常需要一天，以便在实验室中准备，增加分析时间和相关成本。在这里，我们描述了一种基于深度学习的虚拟HER2 IHC染色方法，其使用条件生成的对抗网络培训，训练以便将未标记/标记的乳房组织部分的自发荧光显微镜图像快速转化为明亮场当量的显微镜图像，匹配标准HER2 IHC染色在相同的组织部分上进行化学进行。通过定量分析证明了这一虚拟HER2染色框架的功效，其中三个董事会认证的乳房病理学家盲目地评级了HER2的几乎染色和免疫化化学染色的HER2整个幻灯片图像（WSIS），揭示了通过检查虚拟来确定的HER2分数IHC图像与其免疫组织化学染色的同类一样准确。通过相同的诊断师进行的第二种定量盲化研究进一步揭示了几乎染色的HER2图像在核细节，膜清晰度和染色伪像相对于其免疫组织化学染色的对应物的染色伪影等级具有相当的染色质量。这种虚拟HER2染色框架在实验室中绕过了昂贵，费力，耗时耗时的IHC染色程序，并且可以扩展到其他类型的生物标志物，以加速生命科学和生物医学工作流程的IHC组织染色。

Graph Neural Networks (GNNs) have shown satisfying performance on various graph learning tasks. To achieve better fitting capability, most GNNs are with a large number of parameters, which makes these GNNs computationally expensive. Therefore, it is difficult to deploy them onto edge devices with scarce computational resources, e.g., mobile phones and wearable smart devices. Knowledge Distillation (KD) is a common solution to compress GNNs, where a light-weighted model (i.e., the student model) is encouraged to mimic the behavior of a computationally expensive GNN (i.e., the teacher GNN model). Nevertheless, most existing GNN-based KD methods lack fairness consideration. As a consequence, the student model usually inherits and even exaggerates the bias from the teacher GNN. To handle such a problem, we take initial steps towards fair knowledge distillation for GNNs. Specifically, we first formulate a novel problem of fair knowledge distillation for GNN-based teacher-student frameworks. Then we propose a principled framework named RELIANT to mitigate the bias exhibited by the student model. Notably, the design of RELIANT is decoupled from any specific teacher and student model structures, and thus can be easily adapted to various GNN-based KD frameworks. We perform extensive experiments on multiple real-world datasets, which corroborates that RELIANT achieves less biased GNN knowledge distillation while maintaining high prediction utility.

Despite significant progress in object categorization, in recent years, a number of important challenges remain; mainly, the ability to learn from limited labeled data and to recognize object classes within large, potentially open, set of labels. Zero-shot learning is one way of addressing these challenges, but it has only been shown to work with limited sized class vocabularies and typically requires separation between supervised and unsupervised classes, allowing former to inform the latter but not vice versa. We propose the notion of vocabulary-informed learning to alleviate the above mentioned challenges and address problems of supervised, zero-shot, generalized zero-shot and open set recognition using a unified framework. Specifically, we propose a weighted maximum margin framework for semantic manifold-based recognition that incorporates distance constraints from (both supervised and unsupervised) vocabulary atoms. Distance constraints ensure that labeled samples are projected closer to their correct prototypes, in the embedding space, than to others. We illustrate that resulting model shows improvements in supervised, zero-shot, generalized zero-shot, and large open set recognition, with up to 310K class vocabulary on Animal with Attributes and ImageNet datasets.

Machine Reading Comprehension has become one of the most advanced and popular research topics in the fields of Natural Language Processing in recent years. The classification of answerability questions is a relatively significant sub-task in machine reading comprehension; however, there haven't been many studies. Retro-Reader is one of the studies that has solved this problem effectively. However, the encoders of most traditional machine reading comprehension models in general and Retro-Reader, in particular, have not been able to exploit the contextual semantic information of the context completely. Inspired by SemBERT, we use semantic role labels from the SRL task to add semantics to pre-trained language models such as mBERT, XLM-R, PhoBERT. This experiment was conducted to compare the influence of semantics on the classification of answerability for the Vietnamese machine reading comprehension. Additionally, we hope this experiment will enhance the encoder for the Retro-Reader model's Sketchy Reading Module. The improved Retro-Reader model's encoder with semantics was first applied to the Vietnamese Machine Reading Comprehension task and obtained positive results.

RTE is a significant problem and is a reasonably active research community. The proposed research works on the approach to this problem are pretty diverse with many different directions. For Vietnamese, the RTE problem is moderately new, but this problem plays a vital role in natural language understanding systems. Currently, methods to solve this problem based on contextual word representation learning models have given outstanding results. However, Vietnamese is a semantically rich language. Therefore, in this paper, we want to present an experiment combining semantic word representation through the SRL task with context representation of BERT relative models for the RTE problem. The experimental results give conclusions about the influence and role of semantic representation on Vietnamese in understanding natural language. The experimental results show that the semantic-aware contextual representation model has about 1% higher performance than the model that does not incorporate semantic representation. In addition, the effects on the data domain in Vietnamese are also higher than those in English. This result also shows the positive influence of SRL on RTE problem in Vietnamese.

To the best of our knowledge, this paper made the first attempt to answer whether word segmentation is necessary for Vietnamese sentiment classification. To do this, we presented five pre-trained monolingual S4- based language models for Vietnamese, including one model without word segmentation, and four models using RDRsegmenter, uitnlp, pyvi, or underthesea toolkits in the pre-processing data phase. According to comprehensive experimental results on two corpora, including the VLSP2016-SA corpus of technical article reviews from the news and social media and the UIT-VSFC corpus of the educational survey, we have two suggestions. Firstly, using traditional classifiers like Naive Bayes or Support Vector Machines, word segmentation maybe not be necessary for the Vietnamese sentiment classification corpus, which comes from the social domain. Secondly, word segmentation is necessary for Vietnamese sentiment classification when word segmentation is used before using the BPE method and feeding into the deep learning model. In this way, the RDRsegmenter is the stable toolkit for word segmentation among the uitnlp, pyvi, and underthesea toolkits.

Advances in computer vision and machine learning techniques have led to significant development in 2D and 3D human pose estimation from RGB cameras, LiDAR, and radars. However, human pose estimation from images is adversely affected by occlusion and lighting, which are common in many scenarios of interest. Radar and LiDAR technologies, on the other hand, need specialized hardware that is expensive and power-intensive. Furthermore, placing these sensors in non-public areas raises significant privacy concerns. To address these limitations, recent research has explored the use of WiFi antennas (1D sensors) for body segmentation and key-point body detection. This paper further expands on the use of the WiFi signal in combination with deep learning architectures, commonly used in computer vision, to estimate dense human pose correspondence. We developed a deep neural network that maps the phase and amplitude of WiFi signals to UV coordinates within 24 human regions. The results of the study reveal that our model can estimate the dense pose of multiple subjects, with comparable performance to image-based approaches, by utilizing WiFi signals as the only input. This paves the way for low-cost, broadly accessible, and privacy-preserving algorithms for human sensing.