国家推进翻译科学中心（NCATS）生物医学数据翻译（译者）旨在衰减翻译科学家面临的问题。翻译是一种多功能架构，包括六个自主中继代理（ARAS）和八个知识提供商（KPS）。在本文中，我们介绍了解释剂（XARA）的设计，是一种基于案例的ARA，通过访问多个KPS，排名结果并解释结果排名来回答生物医学查询。解释性代理设计有五个知识集装箱，包括四个原始知识容器和一个用于解释的额外容器 - 解释容器。解释容器是基于案例的，并设计有自己的知识容器。

Radiance Fields (RF) are popular to represent casually-captured scenes for new view generation and have been used for applications beyond it. Understanding and manipulating scenes represented as RFs have to naturally follow to facilitate mixed reality on personal spaces. Semantic segmentation of objects in the 3D scene is an important step for that. Prior segmentation efforts using feature distillation show promise but don't scale to complex objects with diverse appearance. We present a framework to interactively segment objects with fine structure. Nearest neighbor feature matching identifies high-confidence regions of the objects using distilled features. Bilateral filtering in a joint spatio-semantic space grows the region to recover accurate segmentation. We show state-of-the-art results of segmenting objects from RFs and compositing them to another scene, changing appearance, etc., moving closer to rich scene manipulation and understanding. Project Page: https://rahul-goel.github.io/isrf/

Dense prediction tasks such as segmentation and detection of pathological entities hold crucial clinical value in the digital pathology workflow. However, obtaining dense annotations on large cohorts is usually tedious and expensive. Contrastive learning (CL) is thus often employed to leverage large volumes of unlabeled data to pre-train the backbone network. To boost CL for dense prediction, some studies have proposed variations of dense matching objectives in pre-training. However, our analysis shows that employing existing dense matching strategies on histopathology images enforces invariance among incorrect pairs of dense features and, thus, is imprecise. To address this, we propose a precise location-based matching mechanism that utilizes the overlapping information between geometric transformations to precisely match regions in two augmentations. Extensive experiments on two pretraining datasets (TCGA-BRCA, NCT-CRC-HE) and three downstream datasets (GlaS, CRAG, BCSS) highlight the superiority of our method in semantic and instance segmentation tasks. Our method outperforms previous dense matching methods by up to 7.2 % in average precision for detection and 5.6 % in average precision for instance segmentation tasks. Additionally, by using our matching mechanism in the three popular contrastive learning frameworks, MoCo-v2, VICRegL and ConCL, the average precision in detection is improved by 0.7 % to 5.2 % and the average precision in segmentation is improved by 0.7 % to 4.0 %, demonstrating its generalizability.

Text classifiers have promising applications in high-stake tasks such as resume screening and content moderation. These classifiers must be fair and avoid discriminatory decisions by being invariant to perturbations of sensitive attributes such as gender or ethnicity. However, there is a gap between human intuition about these perturbations and the formal similarity specifications capturing them. While existing research has started to address this gap, current methods are based on hardcoded word replacements, resulting in specifications with limited expressivity or ones that fail to fully align with human intuition (e.g., in cases of asymmetric counterfactuals). This work proposes novel methods for bridging this gap by discovering expressive and intuitive individual fairness specifications. We show how to leverage unsupervised style transfer and GPT-3's zero-shot capabilities to automatically generate expressive candidate pairs of semantically similar sentences that differ along sensitive attributes. We then validate the generated pairs via an extensive crowdsourcing study, which confirms that a lot of these pairs align with human intuition about fairness in the context of toxicity classification. Finally, we show how limited amounts of human feedback can be leveraged to learn a similarity specification that can be used to train downstream fairness-aware models.

Stylized view generation of scenes captured casually using a camera has received much attention recently. The geometry and appearance of the scene are typically captured as neural point sets or neural radiance fields in the previous work. An image stylization method is used to stylize the captured appearance by training its network jointly or iteratively with the structure capture network. The state-of-the-art SNeRF method trains the NeRF and stylization network in an alternating manner. These methods have high training time and require joint optimization. In this work, we present StyleTRF, a compact, quick-to-optimize strategy for stylized view generation using TensoRF. The appearance part is fine-tuned using sparse stylized priors of a few views rendered using the TensoRF representation for a few iterations. Our method thus effectively decouples style-adaption from view capture and is much faster than the previous methods. We show state-of-the-art results on several scenes used for this purpose.

Indian e-commerce industry has evolved over the last decade and is expected to grow over the next few years. The focus has now shifted to turnaround time (TAT) due to the emergence of many third-party logistics providers and higher customer expectations. The key consideration for delivery providers is to balance their overall operating costs while meeting the promised TAT to their customers. E-commerce delivery partners operate through a network of facilities whose strategic locations help to run the operations efficiently. In this work, we identify the locations of hubs throughout the country and their corresponding mapping with the distribution centers. The objective is to minimize the total network costs with TAT adherence. We use Genetic Algorithm and leverage business constraints to reduce the solution search space and hence the solution time. The results indicate an improvement of 9.73% in TAT compliance compared with the current scenario.

Active target sensing is the task of discovering and classifying an unknown number of targets in an environment and is critical in search-and-rescue missions. This paper develops a deep reinforcement learning approach to plan informative trajectories that increase the likelihood for an uncrewed aerial vehicle (UAV) to discover missing targets. Our approach efficiently (1) explores the environment to discover new targets, (2) exploits its current belief of the target states and incorporates inaccurate sensor models for high-fidelity classification, and (3) generates dynamically feasible trajectories for an agile UAV by employing a motion primitive library. Extensive simulations on randomly generated environments show that our approach is more efficient in discovering and classifying targets than several other baselines. A unique characteristic of our approach, in contrast to heuristic informative path planning approaches, is that it is robust to varying amounts of deviations of the prior belief from the true target distribution, thereby alleviating the challenge of designing heuristics specific to the application conditions.

Modern virtual assistants use internal semantic parsing engines to convert user utterances to actionable commands. However, prior work has demonstrated that semantic parsing is a difficult multilingual transfer task with low transfer efficiency compared to other tasks. In global markets such as India and Latin America, this is a critical issue as switching between languages is prevalent for bilingual users. In this work we dramatically improve the zero-shot performance of a multilingual and codeswitched semantic parsing system using two stages of multilingual alignment. First, we show that constrastive alignment pretraining improves both English performance and transfer efficiency. We then introduce a constrained optimization approach for hyperparameter-free adversarial alignment during finetuning. Our Doubly Aligned Multilingual Parser (DAMP) improves mBERT transfer performance by 3x, 6x, and 81x on the Spanglish, Hinglish and Multilingual Task Oriented Parsing benchmarks respectively and outperforms XLM-R and mT5-Large using 3.2x fewer parameters.

In molecular research, simulation \& design of molecules are key areas with significant implications for drug development, material science, and other fields. Current classical computational power falls inadequate to simulate any more than small molecules, let alone protein chains on hundreds of peptide. Therefore these experiment are done physically in wet-lab, but it takes a lot of time \& not possible to examine every molecule due to the size of the search area, tens of billions of dollars are spent every year in these research experiments. Molecule simulation \& design has lately advanced significantly by machine learning models, A fresh perspective on the issue of chemical synthesis is provided by deep generative models for graph-structured data. By optimising differentiable models that produce molecular graphs directly, it is feasible to avoid costly search techniques in the discrete and huge space of chemical structures. But these models also suffer from computational limitations when dimensions become huge and consume huge amount of resources. Quantum Generative machine learning in recent years have shown some empirical results promising significant advantages over classical counterparts.

A major direction in differentially private machine learning is differentially private fine-tuning: pretraining a model on a source of "public data" and transferring the extracted features to downstream tasks. This is an important setting because many industry deployments fine-tune publicly available feature extractors on proprietary data for downstream tasks. In this paper, we use features extracted from state-of-the-art open source models to solve benchmark tasks in computer vision and natural language processing using differentially private fine-tuning. Our key insight is that by accelerating training, we can quickly drive the model parameters to regions in parameter space where the impact of noise is minimized. In doing so, we recover the same performance as non-private fine-tuning for realistic values of epsilon in [0.01, 1.0] on benchmark image classification datasets including CIFAR100.