Federated learning (FL) is a machine learning setting where many clients (e.g. mobile devices or whole organizations) collaboratively train a model under the orchestration of a central server (e.g. service provider), while keeping the training data decentralized. FL embodies the principles of focused data collection and minimization, and can mitigate many of the systemic privacy risks and costs resulting from traditional, centralized machine learning and data science approaches. Motivated by the explosive growth in FL research, this paper discusses recent advances and presents an extensive collection of open problems and challenges.

Federated Learning is a machine learning setting where the goal is to train a highquality centralized model while training data remains distributed over a large number of clients each with unreliable and relatively slow network connections. We consider learning algorithms for this setting where on each round, each client independently computes an update to the current model based on its local data, and communicates this update to a central server, where the client-side updates are aggregated to compute a new global model. The typical clients in this setting are mobile phones, and communication efficiency is of the utmost importance. In this paper, we propose two ways to reduce the uplink communication costs: structured updates, where we directly learn an update from a restricted space parametrized using a smaller number of variables, e.g. either low-rank or a random mask; and sketched updates, where we learn a full model update and then compress it using a combination of quantization, random rotations, and subsampling before sending it to the server. Experiments on both convolutional and recurrent networks show that the proposed methods can reduce the communication cost by two orders of magnitude. * Work performed while also affiliated with University of Edinburgh.

解释在人类学习中发挥着相当大的作用，特别是在仍然在形成抽象的主要挑战，以及了解世界的关系和因果结构的地区。在这里，我们探索强化学习代理人是否同样可以从解释中受益。我们概述了一系列关系任务，涉及选择一个在一个集合中奇数一个的对象（即，沿许多可能的特征尺寸之一的唯一）。奇数一张任务要求代理在一组对象中的多维关系上推理。我们展示了代理商不会仅从奖励中学习这些任务，但是当它们也培训以生成语言解释对象属性或选择正确或不正确时，实现> 90％的性能。在进一步的实验中，我们展示了预测的解释如何使代理能够从模糊，因果困难的训练中适当地推广，甚至可以学习执行实验干预以识别因果结构。我们表明解释有助于克服代理人来解决简单特征的趋势，并探讨解释的哪些方面使它们成为最有益的。我们的结果表明，从解释中学习是一种强大的原则，可以为培训更强大和一般机器学习系统提供有希望的道路。

Magnetic Resonance Fingerprinting (MRF) is an efficient quantitative MRI technique that can extract important tissue and system parameters such as T1, T2, B0, and B1 from a single scan. This property also makes it attractive for retrospectively synthesizing contrast-weighted images. In general, contrast-weighted images like T1-weighted, T2-weighted, etc., can be synthesized directly from parameter maps through spin-dynamics simulation (i.e., Bloch or Extended Phase Graph models). However, these approaches often exhibit artifacts due to imperfections in the mapping, the sequence modeling, and the data acquisition. Here we propose a supervised learning-based method that directly synthesizes contrast-weighted images from the MRF data without going through the quantitative mapping and spin-dynamics simulation. To implement our direct contrast synthesis (DCS) method, we deploy a conditional Generative Adversarial Network (GAN) framework and propose a multi-branch U-Net as the generator. The input MRF data are used to directly synthesize T1-weighted, T2-weighted, and fluid-attenuated inversion recovery (FLAIR) images through supervised training on paired MRF and target spin echo-based contrast-weighted scans. In-vivo experiments demonstrate excellent image quality compared to simulation-based contrast synthesis and previous DCS methods, both visually as well as by quantitative metrics. We also demonstrate cases where our trained model is able to mitigate in-flow and spiral off-resonance artifacts that are typically seen in MRF reconstructions and thus more faithfully represent conventional spin echo-based contrast-weighted images.

We present IMAS, a method that segments the primary objects in videos without manual annotation in training or inference. Previous methods in unsupervised video object segmentation (UVOS) have demonstrated the effectiveness of motion as either input or supervision for segmentation. However, motion signals may be uninformative or even misleading in cases such as deformable objects and objects with reflections, causing unsatisfactory segmentation. In contrast, IMAS achieves Improved UVOS with Motion-Appearance Synergy. Our method has two training stages: 1) a motion-supervised object discovery stage that deals with motion-appearance conflicts through a learnable residual pathway; 2) a refinement stage with both low- and high-level appearance supervision to correct model misconceptions learned from misleading motion cues. Additionally, we propose motion-semantic alignment as a model-agnostic annotation-free hyperparam tuning method. We demonstrate its effectiveness in tuning critical hyperparams previously tuned with human annotation or hand-crafted hyperparam-specific metrics. IMAS greatly improves the segmentation quality on several common UVOS benchmarks. For example, we surpass previous methods by 8.3% on DAVIS16 benchmark with only standard ResNet and convolutional heads. We intend to release our code for future research and applications.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Dry Eye Disease (DED) is one of the most common ocular diseases: over five percent of US adults suffer from DED. Tear film instability is a known factor for DED, and is thought to be regulated in large part by the thin lipid layer that covers and stabilizes the tear film. In order to aid eye related disease diagnosis, this work proposes a novel paradigm in using computer vision techniques to numerically analyze the tear film lipid layer (TFLL) spread. Eleven videos of the tear film lipid layer spread are collected with a micro-interferometer and a subset are annotated. A tracking algorithm relying on various pillar computer vision techniques is developed. Our method can be found at https://easytear-dev.github.io/.

Large language models (LLMs) have led to a series of breakthroughs in natural language processing (NLP), owing to their excellent understanding and generation abilities. Remarkably, what further sets these models apart is the massive amounts of world knowledge they internalize during pretraining. While many downstream applications provide the model with an informational context to aid its performance on the underlying task, how the model's world knowledge interacts with the factual information presented in the context remains under explored. As a desirable behavior, an LLM should give precedence to the context whenever it contains task-relevant information that conflicts with the model's memorized knowledge. This enables model predictions to be grounded in the context, which can then be used to update or correct specific model predictions without frequent retraining. By contrast, when the context is irrelevant to the task, the model should ignore it and fall back on its internal knowledge. In this paper, we undertake a first joint study of the aforementioned two properties, namely controllability and robustness, in the context of LLMs. We demonstrate that state-of-the-art T5 and PaLM (both pretrained and finetuned) could exhibit poor controllability and robustness, which do not scale with increasing model size. As a solution, we propose a novel method - Knowledge Aware FineTuning (KAFT) - to strengthen both controllability and robustness by incorporating counterfactual and irrelevant contexts to standard supervised datasets. Our comprehensive evaluation showcases the utility of KAFT across model architectures and sizes.

ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。

草图在快速执行的徒手绘图时会形成直观而有力的视觉表达。我们提出了一种从场景草图中综合现实照片的方法。不需要草图和照片对，我们的框架直接以无监督的方式从随时可用的大型照片数据集中学习。为此，我们引入了一个标准化模块，该模块在训练期间通过将照片和草图转换为标准化域，即边缘地图，从而提供伪素描 - 光谱对。草图和照片之间的域间隙减少也使我们可以将它们分为两个组成部分：整体场景结构和低级视觉样式，例如颜色和纹理。利用这一优势，我们通过结合草图的结构和参考照片的视觉样式来合成照片真实的图像。关于感知相似性指标和人类感知研究的广泛实验结果表明，该方法可以从场景草图和跑赢大于最先进的照片合成基准中产生逼真的照片。我们还证明，我们的框架通过编辑相应草图的笔触来促进对照片综合的可控操作，从而比依赖于区域级编辑的以前的方法提供了更多细粒度的细节。