Tuberculosis (TB), an infectious bacterial disease, is a significant cause of death, especially in low-income countries, with an estimated ten million new cases reported globally in $2020$. While TB is treatable, non-adherence to the medication regimen is a significant cause of morbidity and mortality. Thus, proactively identifying patients at risk of dropping off their medication regimen enables corrective measures to mitigate adverse outcomes. Using a proxy measure of extreme non-adherence and a dataset of nearly $700,000$ patients from four states in India, we formulate and solve the machine learning (ML) problem of early prediction of non-adherence based on a custom rank-based metric. We train ML models and evaluate against baselines, achieving a $\sim 100\%$ lift over rule-based baselines and $\sim 214\%$ over a random classifier, taking into account country-wide large-scale future deployment. We deal with various issues in the process, including data quality, high-cardinality categorical data, low target prevalence, distribution shift, variation across cohorts, algorithmic fairness, and the need for robustness and explainability. Our findings indicate that risk stratification of non-adherent patients is a viable, deployable-at-scale ML solution.
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The rise in data has led to the need for dimension reduction techniques, especially in the area of non-scalar variables, including time series, natural language processing, and computer vision. In this paper, we specifically investigate dimension reduction for time series through functional data analysis. Current methods for dimension reduction in functional data are functional principal component analysis and functional autoencoders, which are limited to linear mappings or scalar representations for the time series, which is inefficient. In real data applications, the nature of the data is much more complex. We propose a non-linear function-on-function approach, which consists of a functional encoder and a functional decoder, that uses continuous hidden layers consisting of continuous neurons to learn the structure inherent in functional data, which addresses the aforementioned concerns in the existing approaches. Our approach gives a low dimension latent representation by reducing the number of functional features as well as the timepoints at which the functions are observed. The effectiveness of the proposed model is demonstrated through multiple simulations and real data examples.
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A comprehensive pharmaceutical recommendation system was designed based on the patients and drugs features extracted from Drugs.com and Druglib.com. First, data from these databases were combined, and a dataset of patients and drug information was built. Secondly, the patients and drugs were clustered, and then the recommendation was performed using different ratings provided by patients, and importantly by the knowledge obtained from patients and drug specifications, and considering drug interactions. To the best of our knowledge, we are the first group to consider patients conditions and history in the proposed approach for selecting a specific medicine appropriate for that particular user. Our approach applies artificial intelligence (AI) models for the implementation. Sentiment analysis using natural language processing approaches is employed in pre-processing along with neural network-based methods and recommender system algorithms for modeling the system. In our work, patients conditions and drugs features are used for making two models based on matrix factorization. Then we used drug interaction to filter drugs with severe or mild interactions with other drugs. We developed a deep learning model for recommending drugs by using data from 2304 patients as a training set, and then we used data from 660 patients as our validation set. After that, we used knowledge from critical information about drugs and combined the outcome of the model into a knowledge-based system with the rules obtained from constraints on taking medicine.
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The United States coastline spans 95,471 miles; a distance that cannot be effectively patrolled or secured by manual human effort alone. Unmanned Aerial Vehicles (UAVs) equipped with infrared cameras and deep-learning based algorithms represent a more efficient alternative for identifying and segmenting objects of interest - namely, ships. However, standard approaches to training these algorithms require large-scale datasets of densely labeled infrared maritime images. Such datasets are not publicly available and manually annotating every pixel in a large-scale dataset would have an extreme labor cost. In this work we demonstrate that, in the context of segmenting ships in infrared imagery, weakly-supervising an algorithm with sparsely labeled data can drastically reduce data labeling costs with minimal impact on system performance. We apply weakly-supervised learning to an unlabeled dataset of 7055 infrared images sourced from the Naval Air Warfare Center Aircraft Division (NAWCAD). We find that by sparsely labeling only 32 points per image, weakly-supervised segmentation models can still effectively detect and segment ships, with a Jaccard score of up to 0.756.
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The paper presents a cross-domain review analysis on four popular review datasets: Amazon, Yelp, Steam, IMDb. The analysis is performed using Hadoop and Spark, which allows for efficient and scalable processing of large datasets. By examining close to 12 million reviews from these four online forums, we hope to uncover interesting trends in sales and customer sentiment over the years. Our analysis will include a study of the number of reviews and their distribution over time, as well as an examination of the relationship between various review attributes such as upvotes, creation time, rating, and sentiment. By comparing the reviews across different domains, we hope to gain insight into the factors that drive customer satisfaction and engagement in different product categories.
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Visual language such as charts and plots is ubiquitous in the human world. Comprehending plots and charts requires strong reasoning skills. Prior state-of-the-art (SOTA) models require at least tens of thousands of training examples and their reasoning capabilities are still much limited, especially on complex human-written queries. This paper presents the first one-shot solution to visual language reasoning. We decompose the challenge of visual language reasoning into two steps: (1) plot-to-text translation, and (2) reasoning over the translated text. The key in this method is a modality conversion module, named as DePlot, which translates the image of a plot or chart to a linearized table. The output of DePlot can then be directly used to prompt a pretrained large language model (LLM), exploiting the few-shot reasoning capabilities of LLMs. To obtain DePlot, we standardize the plot-to-table task by establishing unified task formats and metrics, and train DePlot end-to-end on this task. DePlot can then be used off-the-shelf together with LLMs in a plug-and-play fashion. Compared with a SOTA model finetuned on more than >28k data points, DePlot+LLM with just one-shot prompting achieves a 24.0% improvement over finetuned SOTA on human-written queries from the task of chart QA.
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Automated offensive language detection is essential in combating the spread of hate speech, particularly in social media. This paper describes our work on Offensive Language Identification in low resource Indic language Marathi. The problem is formulated as a text classification task to identify a tweet as offensive or non-offensive. We evaluate different mono-lingual and multi-lingual BERT models on this classification task, focusing on BERT models pre-trained with social media datasets. We compare the performance of MuRIL, MahaTweetBERT, MahaTweetBERT-Hateful, and MahaBERT on the HASOC 2022 test set. We also explore external data augmentation from other existing Marathi hate speech corpus HASOC 2021 and L3Cube-MahaHate. The MahaTweetBERT, a BERT model, pre-trained on Marathi tweets when fine-tuned on the combined dataset (HASOC 2021 + HASOC 2022 + MahaHate), outperforms all models with an F1 score of 98.43 on the HASOC 2022 test set. With this, we also provide a new state-of-the-art result on HASOC 2022 / MOLD v2 test set.
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Free-text rationales (FTRs) follow how humans communicate by explaining reasoning processes via natural language. A number of recent works have studied how to improve language model (LM) generalization by using FTRs to teach LMs the correct reasoning processes behind correct task outputs. These prior works aim to learn from FTRs by appending them to the LM input or target output, but this may introduce an input distribution shift or conflict with the task objective, respectively. We propose KNIFE, which distills FTR knowledge from an FTR-augmented teacher LM (takes both task input and FTR) to a student LM (takes only task input), which is used for inference. Crucially, the teacher LM's forward computation has a bottleneck stage in which all of its FTR states are masked out, which pushes knowledge from the FTR states into the task input/output states. Then, FTR knowledge is distilled to the student LM by training its task input/output states to align with the teacher LM's. On two question answering datasets, we show that KNIFE significantly outperforms existing FTR learning methods, in both fully-supervised and low-resource settings.
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Visual language data such as plots, charts, and infographics are ubiquitous in the human world. However, state-of-the-art vision-language models do not perform well on these data. We propose MatCha (Math reasoning and Chart derendering pretraining) to enhance visual language models' capabilities in jointly modeling charts/plots and language data. Specifically, we propose several pretraining tasks that cover plot deconstruction and numerical reasoning which are the key capabilities in visual language modeling. We perform the MatCha pretraining starting from Pix2Struct, a recently proposed image-to-text visual language model. On standard benchmarks such as PlotQA and ChartQA, the MatCha model outperforms state-of-the-art methods by as much as nearly 20%. We also examine how well MatCha pretraining transfers to domains such as screenshots, textbook diagrams, and document figures and observe overall improvement, verifying the usefulness of MatCha pretraining on broader visual language tasks.
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The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.
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