Diabetic Retinopathy (DR) is a leading cause of vision loss in the world, and early DR detection is necessary to prevent vision loss and support an appropriate treatment. In this work, we leverage interactive machine learning and introduce a joint learning framework, termed DRG-Net, to effectively learn both disease grading and multi-lesion segmentation. Our DRG-Net consists of two modules: (i) DRG-AI-System to classify DR Grading, localize lesion areas, and provide visual explanations; (ii) DRG-Expert-Interaction to receive feedback from user-expert and improve the DRG-AI-System. To deal with sparse data, we utilize transfer learning mechanisms to extract invariant feature representations by using Wasserstein distance and adversarial learning-based entropy minimization. Besides, we propose a novel attention strategy at both low- and high-level features to automatically select the most significant lesion information and provide explainable properties. In terms of human interaction, we further develop DRG-Net as a tool that enables expert users to correct the system's predictions, which may then be used to update the system as a whole. Moreover, thanks to the attention mechanism and loss functions constraint between lesion features and classification features, our approach can be robust given a certain level of noise in the feedback of users. We have benchmarked DRG-Net on the two largest DR datasets, i.e., IDRID and FGADR, and compared it to various state-of-the-art deep learning networks. In addition to outperforming other SOTA approaches, DRG-Net is effectively updated using user feedback, even in a weakly-supervised manner.

Collecting large-scale medical datasets with fully annotated samples for training of deep networks is prohibitively expensive, especially for 3D volume data. Recent breakthroughs in self-supervised learning (SSL) offer the ability to overcome the lack of labeled training samples by learning feature representations from unlabeled data. However, most current SSL techniques in the medical field have been designed for either 2D images or 3D volumes. In practice, this restricts the capability to fully leverage unlabeled data from numerous sources, which may include both 2D and 3D data. Additionally, the use of these pre-trained networks is constrained to downstream tasks with compatible data dimensions. In this paper, we propose a novel framework for unsupervised joint learning on 2D and 3D data modalities. Given a set of 2D images or 2D slices extracted from 3D volumes, we construct an SSL task based on a 2D contrastive clustering problem for distinct classes. The 3D volumes are exploited by computing vectored embedding at each slice and then assembling a holistic feature through deformable self-attention mechanisms in Transformer, allowing incorporating long-range dependencies between slices inside 3D volumes. These holistic features are further utilized to define a novel 3D clustering agreement-based SSL task and masking embedding prediction inspired by pre-trained language models. Experiments on downstream tasks, such as 3D brain segmentation, lung nodule detection, 3D heart structures segmentation, and abnormal chest X-ray detection, demonstrate the effectiveness of our joint 2D and 3D SSL approach. We improve plain 2D Deep-ClusterV2 and SwAV by a significant margin and also surpass various modern 2D and 3D SSL approaches.

数值验证是机器学习研究的核心，因为它允许评估新方法的实际影响，并确认理论和实践之间的一致性。然而，该领域的快速发展构成了一些挑战：研究人员面临着大量的方法来比较，有限的透明度和最佳实践的共识以及乏味的重新实施工作。结果，验证通常是非常部分的，这可能会导致错误的结论，从而减慢研究的进展。我们提出了Benchopt，这是一个协作框架，旨在在跨编程语言和硬件体系结构的机器学习中自动化，复制和发布优化基准。 Benchopt通过提供用于运行，共享和扩展实验的现成工具来简化社区的基准测试。为了展示其广泛的可用性，我们在三个标准学习任务上展示基准：$ \ ell_2 $ regulaine的逻辑回归，套索和RESNET18用于图像分类的培训。这些基准强调了关键的实际发现，这些发现对这些问题的最新问题更加细微，这表明在实际评估中，魔鬼在细节上。我们希望Benchopt能在社区中促进合作工作，从而改善研究结果的可重复性。

在本文中，我们研究了一个通用贝叶斯估计的学习率，在一个通用的环境中，假设类可以是不可数的并且具有不规则形状，损失函数可以具有重尾，最佳假设可能不是唯一的。我们证明，在多尺寸的伯尔尼斯坦的病情下，广义的后验分布集中在最佳假设围绕和广义贝叶斯估计器可以实现快速学习率。我们的结果适用于标准贝叶斯线性回归对重尾部分布稳健。

Recent development in the field of explainable artificial intelligence (XAI) has helped improve trust in Machine-Learning-as-a-Service (MLaaS) systems, in which an explanation is provided together with the model prediction in response to each query. However, XAI also opens a door for adversaries to gain insights into the black-box models in MLaaS, thereby making the models more vulnerable to several attacks. For example, feature-based explanations (e.g., SHAP) could expose the top important features that a black-box model focuses on. Such disclosure has been exploited to craft effective backdoor triggers against malware classifiers. To address this trade-off, we introduce a new concept of achieving local differential privacy (LDP) in the explanations, and from that we establish a defense, called XRand, against such attacks. We show that our mechanism restricts the information that the adversary can learn about the top important features, while maintaining the faithfulness of the explanations.

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make their predictions remains a significant challenge, but explainability tools help provide insights into what models have learned when corresponding histologic features are poorly defined. Here, we present a method for improving explainability of DNN models using synthetic histology generated by a conditional generative adversarial network (cGAN). We show that cGANs generate high-quality synthetic histology images that can be leveraged for explaining DNN models trained to classify molecularly-subtyped tumors, exposing histologic features associated with molecular state. Fine-tuning synthetic histology through class and layer blending illustrates nuanced morphologic differences between tumor subtypes. Finally, we demonstrate the use of synthetic histology for augmenting pathologist-in-training education, showing that these intuitive visualizations can reinforce and improve understanding of histologic manifestations of tumor biology.

Recognizing handwriting images is challenging due to the vast variation in writing style across many people and distinct linguistic aspects of writing languages. In Vietnamese, besides the modern Latin characters, there are accent and letter marks together with characters that draw confusion to state-of-the-art handwriting recognition methods. Moreover, as a low-resource language, there are not many datasets for researching handwriting recognition in Vietnamese, which makes handwriting recognition in this language have a barrier for researchers to approach. Recent works evaluated offline handwriting recognition methods in Vietnamese using images from an online handwriting dataset constructed by connecting pen stroke coordinates without further processing. This approach obviously can not measure the ability of recognition methods effectively, as it is trivial and may be lack of features that are essential in offline handwriting images. Therefore, in this paper, we propose the Transferring method to construct a handwriting image dataset that associates crucial natural attributes required for offline handwriting images. Using our method, we provide a first high-quality synthetic dataset which is complex and natural for efficiently evaluating handwriting recognition methods. In addition, we conduct experiments with various state-of-the-art methods to figure out the challenge to reach the solution for handwriting recognition in Vietnamese.

Image captioning is currently a challenging task that requires the ability to both understand visual information and use human language to describe this visual information in the image. In this paper, we propose an efficient way to improve the image understanding ability of transformer-based method by extending Object Relation Transformer architecture with Attention on Attention mechanism. Experiments on the VieCap4H dataset show that our proposed method significantly outperforms its original structure on both the public test and private test of the Image Captioning shared task held by VLSP.

By utilizing only depth information, the paper introduces a novel but efficient local planning approach that enhances not only computational efficiency but also planning performances for memoryless local planners. The sampling is first proposed to be based on the depth data which can identify and eliminate a specific type of in-collision trajectories in the sampled motion primitive library. More specifically, all the obscured primitives' endpoints are found through querying the depth values and excluded from the sampled set, which can significantly reduce the computational workload required in collision checking. On the other hand, we furthermore propose a steering mechanism also based on the depth information to effectively prevent an autonomous vehicle from getting stuck when facing a large convex obstacle, providing a higher level of autonomy for a planning system. Our steering technique is theoretically proved to be complete in scenarios of convex obstacles. To evaluate effectiveness of the proposed DEpth based both Sampling and Steering (DESS) methods, we implemented them in the synthetic environments where a quadrotor was simulated flying through a cluttered region with multiple size-different obstacles. The obtained results demonstrate that the proposed approach can considerably decrease computing time in local planners, where more trajectories can be evaluated while the best path with much lower cost can be found. More importantly, the success rates calculated by the fact that the robot successfully navigated to the destinations in different testing scenarios are always higher than 99.6% on average.

预测基金绩效对投资者和基金经理都是有益的，但这是一项艰巨的任务。在本文中，我们测试了深度学习模型是否比传统统计技术更准确地预测基金绩效。基金绩效通常通过Sharpe比率进行评估，该比例代表了风险调整的绩效，以确保基金之间有意义的可比性。我们根据每月收益率数据序列数据计算了年度夏普比率，该数据的时间序列数据为600多个投资于美国上市大型股票的开放式共同基金投资。我们发现，经过现代贝叶斯优化训练的长期短期记忆（LSTM）和封闭式复发单元（GRUS）深度学习方法比传统统计量相比，预测基金的Sharpe比率更高。结合了LSTM和GRU的预测的合奏方法，可以实现所有模型的最佳性能。有证据表明，深度学习和结合能提供有希望的解决方案，以应对基金绩效预测的挑战。